Overview

  • Product nameAnti-ASF1a antibody
    See all ASF1A primary antibodies
  • Description
    Rabbit polyclonal to ASF1a
  • SpecificityThis antibody may cross-react with ASF1 beta.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide: SNPRVTRFH INWEDNTEKL EDAESSNPN L, corresponding to internal sequence amino acids 141-170 of Human ASF1a

  • Positive control
    • Jurkat cell extract

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab69935 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 23 kDa (predicted molecular weight: 23 kDa).
ELISA 1/20000.

Target

  • FunctionHistone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
  • Tissue specificityUbiquitously expressed.
  • Sequence similaritiesBelongs to the ASF1 family.
  • Post-translational
    modifications
    Phosphorylated by TLK1 and TLK2. Highly phosphorylated in S-phase and at lower levels in M-phase.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Anti silencing function 1A antibody
    • Anti-silencing function protein 1 homolog A antibody
    • ASF1 anti silencing function 1 homolog A (S. cerevisiae) antibody
    • ASF1 anti silencing function 1 homolog A antibody
    • asf1a antibody
    • ASF1A_HUMAN antibody
    • CCG1 interacting factor A antibody
    • CCG1-interacting factor A antibody
    • CGI 98 antibody
    • CIA antibody
    • hAsf1 antibody
    • hAsf1a antibody
    • hCIA antibody
    • Histone chaperone ASF1A antibody
    • HSPC146 antibody
    see all

Anti-ASF1a antibody images

  • All lanes : Anti-ASF1a antibody (ab69935) at 1/500 dilution

    Lane 1 : Jurkat cell extract
    Lane 2 : Jurkat cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 23 kDa
    Observed band size : 23 kDa

References for Anti-ASF1a antibody (ab69935)

ab69935 has not yet been referenced specifically in any publications.

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