Overview

  • Product nameAnti-ASH2L antibody
    See all ASH2L primary antibodies
  • Description
    Rabbit polyclonal to ASH2L
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a sequence surrounding amino acids 620-624 (G-R-R-S-P) of Human ASH2L (NP_004665.2).

  • Positive control
    • HL60 cell extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab119414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 65, 80 kDa (predicted molecular weight: 69 kDa).

Target

  • FunctionComponent of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
  • Tissue specificityUbiquitously expressed. Predominantly expressed in adult heart and testis and fetal lung and liver, with barely detectable expression in adult lung, liver, kidney, prostate, and peripheral leukocytes.
  • Sequence similaritiesContains 1 B30.2/SPRY domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • ASH 2 antibody
    • Ash2 (absent small or homeotic) like antibody
    • Ash2 (absent, small, or homeotic) like (Drosophila) antibody
    • ASH2 antibody
    • ASH2 LIKE antibody
    • ASH2 like protein antibody
    • ASH2-like protein antibody
    • Ash2l antibody
    • ASH2L_HUMAN antibody
    • ASH2L1 antibody
    • ASH2L2 antibody
    • Bre 2 antibody
    • Bre2 antibody
    • Discs 2-like antibody
    • Drosophila absent, small, or homeotic antibody
    • Drosophila ASH2-like antibody
    • Set1/Ash2 histone methyltransferase complex subunit ASH2 antibody
    see all

Anti-ASH2L antibody images

  • Anti-ASH2L antibody (ab119414) at 1/500 dilution + HL60 cell extract

    Predicted band size : 69 kDa

References for Anti-ASH2L antibody (ab119414)

ab119414 has not yet been referenced specifically in any publications.

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