Anti-ASK1 (phospho S83) antibody - Azide free (ab14380)

Overview

  • Product nameAnti-ASK1 (phospho S83) antibody - Azide free
    See all ASK1 primary antibodies
  • Description
    Rabbit polyclonal to ASK1 (phospho S83) - Azide free
  • SpecificityDetects overexpressed ASK1 only when phosphorylated at Ser83.
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human)corresponding to residues around Ser83 of human ASK1 conjugated to KLH.

Properties

Applications

Our Abpromise guarantee covers the use of ab14380 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 155 kDa.
IP 1/100.

Target

  • FunctionComponent of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
  • Tissue specificityAbundantly expressed in heart and pancreas.
  • Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Dephosphorylated and activated by PGAM5.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apoptosis signal regulating kinase 1 antibody
    • Apoptosis signal-regulating kinase 1 antibody
    • ASK 1 antibody
    • ASK-1 antibody
    • ASK1 antibody
    • M3K5 antibody
    • M3K5_HUMAN antibody
    • MAP/ERK kinase kinase 5 antibody
    • MAP3K5 antibody
    • MAPK/ERK kinase kinase 5 antibody
    • MAPKKK5 antibody
    • MEK kinase 5 antibody
    • MEKK 5 antibody
    • MEKK5 antibody
    • Mitogen activated protein kinase kinase kinase 5 antibody
    • Mitogen-activated protein kinase kinase kinase 5 antibody
    see all

References for Anti-ASK1 (phospho S83) antibody - Azide free (ab14380)

ab14380 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your email. Regarding ab14380, I double-checked with the source of this antibody and we do believe that the antibody will not be able to detect endogenous ASK1. As stated on the datasheet, "Detects overexpressed ASK1 only when phosphoryla...

Read More

Thank you for your enquiry. Ab14380 detects overexpressed ASK1 only when phosphorylated at Ser83. Ab5689 - a band of 155 kDa was detected using SW1353 whole cell lysate. If you have any additional questions, please contact us again.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"