Overview

  • Product name
    Anti-ASXL1 antibody [2049C2a]
    See all ASXL1 primary antibodies
  • Description
    Mouse monoclonal [2049C2a] to ASXL1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment of ASXL1 (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab50817 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 165 kDa.

Target

  • Function
    Probable Polycomb group (PcG) protein. Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1).
  • Tissue specificity
    Widely expressed at low level. Expressed in heart, brain, skeletal muscle, placenta, pancreas, spleen, prostate, small intestine, colon, peripheral blood, leukocytes, bone marrow and fetal liver. Highly expressed in testes.
  • Sequence similarities
    Belongs to the Asx family.
    Contains 1 PHD-type zinc finger.
  • Domain
    Contains one Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, which may be required for an association with nuclear receptors.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Additional sex combs like 1 (Drosophila) antibody
    • Additional sex combs like protein 1 antibody
    • Additional sex combs-like protein 1 antibody
    • ASXL1 antibody
    • ASXL1_HUMAN antibody
    • KIAA0978 antibody
    • Putative Polycomb group protein ASXL1 antibody
    see all

Anti-ASXL1 antibody [2049C2a] images

References for Anti-ASXL1 antibody [2049C2a] (ab50817)

This product has been referenced in:
  • Balasubramani A  et al. Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex. Nat Commun 6:7307 (2015). WB ; Mouse . Read more (PubMed: 26095772) »

See 1 Publication for this product

Product Wall

I have continued to look through our catalogue and I cannot find any kits that would allow you to conjugate an antibody to Protein A/G beads. I did however find this kit which may work: Please let me know if there is anything else I can h...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up