Overview

  • Product name
  • Description
    Rabbit polyclonal to ATAD2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Horse, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 1205-1254 (TQDTSVDHNE TGNTGESSVE ENEKQQNASE SKLELRNNSN TCNIENELED) of Human ATAD2 (NP_054828).

  • Positive control
    • MCF7 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab118664 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 159 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
  • Tissue specificity
    Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors.
  • Sequence similarities
    Belongs to the AAA ATPase family.
    Contains 1 bromo domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AAA nuclear coregulator cancer-associated protein antibody
    • AAA nuclear coregulator, cancer-associated antibody
    • ANCCA antibody
    • Atad2 antibody
    • ATAD2_HUMAN antibody
    • ATPase family AAA domain containing 2 antibody
    • ATPase family AAA domain containing protein 2 antibody
    • ATPase family AAA domain-containing protein 2 antibody
    • CT137 antibody
    • DKFZp667N1320 antibody
    • L16 antibody
    • MGC131938 antibody
    • MGC142216 antibody
    • MGC29843 antibody
    • MGC5254 antibody
    • PRO2000 antibody
    see all

Images

  • Anti-ATAD2 antibody (ab118664) at 1 µg/ml + MCF7 cell lysate at 10 µg

    Predicted band size : 159 kDa

References

ab118664 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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