Overview

  • Product nameAnti-ATAD2 antibody
    See all ATAD2 primary antibodies
  • Description
    Mouse polyclonal to ATAD2
  • SpecificityThis antibody is reactive against mammalian transfected lysate.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    ATAD2 (AAH19909.1, 1 a.a. ~ 362 a.a) full-length human protein.

  • Positive control
    • Transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab68019 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 45 kDa.

Target

  • FunctionMay be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
  • Tissue specificityHighly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors.
  • Sequence similaritiesBelongs to the AAA ATPase family.
    Contains 1 bromo domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AAA nuclear coregulator cancer-associated protein antibody
    • AAA nuclear coregulator, cancer-associated antibody
    • ANCCA antibody
    • Atad2 antibody
    • ATAD2_HUMAN antibody
    • ATPase family AAA domain containing 2 antibody
    • ATPase family AAA domain containing protein 2 antibody
    • ATPase family AAA domain-containing protein 2 antibody
    • CT137 antibody
    • DKFZp667N1320 antibody
    • L16 antibody
    • MGC131938 antibody
    • MGC142216 antibody
    • MGC29843 antibody
    • MGC5254 antibody
    • PRO2000 antibody
    see all

Anti-ATAD2 antibody images

  • All lanes : Anti-ATAD2 antibody (ab68019) at 1/500 dilution

    Lane 1 : ATAD2 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 1/500 dilution per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Observed band size : 45 kDa (why is the actual band size different from the predicted?)

References for Anti-ATAD2 antibody (ab68019)

ab68019 has not yet been referenced specifically in any publications.

Product Wall

The antibody was raised against recombinant ATAD2, instead of overexpressed and purified protein.



The immunogen corresponds to the full length sequence found at the GenBank accession below-

http://www.ncbi.nlm.nih.gov/protein/AAH19909.1

This corresponds to the amino acids numbered 1029 to 1390 on the UniProt accession-...

Read More

Thank you for contacting us. This antibody was raised against AAH19909.1 which is a human ATAD2 sequence with an alternative initiation and therefore a lower molecular weight (~40kDa). The WB image was generated using 293T cells transfected with ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"