Overview

  • Product name
    Anti-ATBF1 antibody
  • Description
    Rabbit polyclonal to ATBF1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to amino acids 517-787 of Human ATBF1 (BC029653)

  • Positive control
    • HeLa, MCF7 and A549 cell lysates and Human fetal brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab119909 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 404 kDa.
IHC-P 1/100 - 1/500.

Target

  • Relevance
    ATBF1 is a transcription factor that negatively regulates alpha fetoprotein and MYB, transactivates CDKN1A, and may be a tumor suppressor. Loss of ATBF1 is one mechanism that defines the absence of growth control in prostate cancer. Presence of the isoform ABTF1-A is correlated with better prognosis in breast cancer and may also serve as a marker of endocrine responsiveness.
  • Cellular localization
    Nuclear
  • Database links
  • Alternative names
    • Alpha fetoprotein enhancer binding protein antibody
    • AT binding transcription factor 1 antibody
    • AT motif binding factor antibody
    • ATBT antibody
    • ZFHX3 antibody
    see all

Images

  • All lanes : Anti-ATBF1 antibody (ab119909) at 1/500 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : MCF7 cell lysate
    Lane 3 : A549 cell lysate


    Predicted band size : 404 kDa
  • Immunohistochemical staining of formalin-fixed, paraffin-embedded Human fetal brain tissue labelled with ab119909 at 1/100 dilution. Note nuclear staining.

References

ab119909 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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