• Product nameAnti-ATF7 antibody
    See all ATF7 primary antibodies
  • Description
    Rabbit polyclonal to ATF7
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 397-446 (HKDCPVTALQ KKTQGYLESP KESSEPTGSP APVIQHSSAT APSNGLSVRS) of Rat ATF7 (NP_001101585).

  • Positive control
    • Rat lung lysate.



Our Abpromise guarantee covers the use of ab123046 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionPlays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.
    Isoform 4/ATF-A0 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter.
  • Tissue specificityExpressed in heart, lung and skeletal muscle. Isoform 4 is expressed in various tissues including heart, brain, placenta, lung and skeletal muscle. Highest levels in skeletal muscle. Lowest in lung and placenta.
  • Sequence similaritiesBelongs to the bZIP family.
    Contains 1 bZIP domain.
    Contains 1 C2H2-type zinc finger.
  • Post-translational
    On EGF stimulation, phosphorylated first on Thr-53 allowing subsequent phosphorylation on Thr-51. This latter phosphorylation prevents sumoylation, increases binding to TAF12 and enhances transcriptional activity.
    Sumoylation delays nuclear localization and inhibits transactivation activity through preventing binding to TAF12. RANBP2 appears to be the specific E3 ligase.
  • Cellular localizationNucleus. Nucleus > nucleoplasm. Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear periphery.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110012F10Rik antibody
    • 9430065F09Rik antibody
    • Activating transcription factor 7 antibody
    • AI549878 antibody
    • ATF7 antibody
    • Atf7 protein antibody
    • ATF7_HUMAN antibody
    • ATFA antibody
    • C130020M04Rik antibody
    • cAMP-dependent transcription factor ATF-7 antibody
    • Cyclic AMP-dependent transcription factor ATF 7 antibody
    • Cyclic AMP-dependent transcription factor ATF-7 antibody
    • MGC31554 antibody
    • MGC57182 antibody
    • Transcription factor ATF A antibody
    • Transcription factor ATF-A antibody
    see all

Anti-ATF7 antibody images

  • Anti-ATF7 antibody (ab123046) at 1 µg/ml + Rat lung lysate at 10 µg

    Predicted band size : 52 kDa

References for Anti-ATF7 antibody (ab123046)

ab123046 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123046.
Please use the links above to contact us or submit feedback about this product.