• Product nameAnti-ATG16L1 antibody
    See all ATG16L1 primary antibodies
  • Description
    Rabbit polyclonal to ATG16L1
  • Tested applicationsSuitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 300-350 of Human ATG16L1 (NP_110430.5).

  • Positive control
    • HeLa whole cell lysate.


Associated products


Our Abpromise guarantee covers the use of ab117816 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
  • Application notesIs unsuitable for WB.
  • Target

    • FunctionPlays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
    • Involvement in diseaseInflammatory bowel disease 10
    • Sequence similaritiesBelongs to the WD repeat ATG16 family.
      Contains 7 WD repeats.
    • Post-translational
      Proteolytic cleavage by activated CASP3 leads to degradation and may regulate autophagy upon cellular stress and apoptotic stimuli.
    • Cellular localizationCytoplasm. Preautophagosomal structure membrane. Recruited to omegasomes membranes by WIPI2. Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. Localizes also to discrete punctae along the ciliary axoneme.
    • Information by UniProt
    • Database links
    • FormThere are 4 isoforms produced by alternative splicing.
    • Alternative names
      • A16L1_HUMAN antibody
      • APG16 like 1 antibody
      • APG16-like 1 antibody
      • APG16L antibody
      • APG16L beta antibody
      • ATG16 autophagy related 16 like 1 antibody
      • ATG16 autophagy related 16-like 1 (S. cerevisiae) antibody
      • ATG16A antibody
      • ATG16L antibody
      • Atg16l1 antibody
      • Autophagy related protein 16 1 antibody
      • Autophagy-related protein 16-1 antibody
      • FLJ00045 antibody
      • FLJ10035 antibody
      • FLJ10828 antibody
      • FLJ22677 antibody
      • IBD10 antibody
      • OTTHUMP00000164391 antibody
      • OTTHUMP00000164393 antibody
      • OTTHUMP00000165876 antibody
      • OTTHUMP00000165877 antibody
      • WD repeat domain 30 antibody
      • WDR30 antibody
      see all

    Anti-ATG16L1 antibody images

    • Detection of Human ATG16L1 in Immunoprecipitates of Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells using ab117816 at 6 µg/mg of lysate (Lane 1). Lane 2 is the IgG immunoprecipitate control. Subsequent WB detection was done using an other anti Human ATG16L1 antibody.

    References for Anti-ATG16L1 antibody (ab117816)

    ab117816 has not yet been referenced specifically in any publications.

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