Overview

  • Product nameAnti-ATG4B antibody
    See all ATG4B primary antibodies
  • Description
    Rabbit polyclonal to ATG4B
  • Tested applicationsSuitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between residue 275 and 325 of Human ATG4B (NP_037457.3).

  • Positive control
    • HeLa whole cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab101983 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
  • Application notesIs unsuitable for WB.
  • Target

    • FunctionCysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
    • Tissue specificityMainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.
    • Sequence similaritiesBelongs to the peptidase C54 family.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • APG4 autophagy 4 homolog B antibody
      • APG4B antibody
      • ATG4 autophagy related 4 homolog B (S. cerevisiae) antibody
      • ATG4B antibody
      • ATG4B_HUMAN antibody
      • AUT like 1 cysteine endopeptidase antibody
      • AUT-like 1 cysteine endopeptidase antibody
      • AUTL1 antibody
      • Autophagin 1 antibody
      • Autophagin-1 antibody
      • Autophagy related cysteine endopeptidase 1 antibody
      • Autophagy related protein 4 homolog B antibody
      • Autophagy-related cysteine endopeptidase 1 antibody
      • Autophagy-related protein 4 homolog B antibody
      • Cysteine protease ATG4B antibody
      • hAPG4B antibody
      • MGC1353 antibody
      see all

    Anti-ATG4B antibody images

    • Detection of ATG4B by Western Blot of Immunprecipitate.
      An antibody to ATG4B, at 1 µg/ml, staining ATG4B in HeLa whole cell lysate immunoprecipitated using ab101983 at 3 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with an exposure time of 30 seconds.

    References for Anti-ATG4B antibody (ab101983)

    ab101983 has not yet been referenced specifically in any publications.

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