• Product nameAnti-ATG4B antibody
    See all ATG4B primary antibodies
  • Description
    Rabbit polyclonal to ATG4B
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from the central region of human ATG4B conjugated to KLH

  • Positive control
    • 293 cell lysates (nontransfected or transiently transfected with the ATG4B gene) and human skeletal muscle tissue.


Associated products


Our Abpromise guarantee covers the use of ab70867 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Detects a band of approximately 44 kDa (predicted molecular weight: 44 kDa).
ELISA 1/1000.
IHC-P 1/10 - 1/50.


  • FunctionCysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
  • Tissue specificityMainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.
  • Sequence similaritiesBelongs to the peptidase C54 family.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • APG4 autophagy 4 homolog B antibody
    • APG4B antibody
    • ATG4 autophagy related 4 homolog B (S. cerevisiae) antibody
    • ATG4B antibody
    • ATG4B_HUMAN antibody
    • AUT like 1 cysteine endopeptidase antibody
    • AUT-like 1 cysteine endopeptidase antibody
    • AUTL1 antibody
    • Autophagin 1 antibody
    • Autophagin-1 antibody
    • Autophagy related cysteine endopeptidase 1 antibody
    • Autophagy related protein 4 homolog B antibody
    • Autophagy-related cysteine endopeptidase 1 antibody
    • Autophagy-related protein 4 homolog B antibody
    • Cysteine protease ATG4B antibody
    • hAPG4B antibody
    • MGC1353 antibody
    see all

Anti-ATG4B antibody images

  • All lanes : Anti-ATG4B antibody (ab70867) at 1/50 dilution

    Lane 1 : 293 cell lysates (nontransfected)
    Lane 2 : 293 cell lysates transiently transfected with the ATG4B gene

    Lysates/proteins at 2 µg per lane.

    Predicted band size : 44 kDa
    Observed band size : 44 kDa
  • abx at 1/10 dilution, staining ATG4B in human skeletal muscle by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining.

References for Anti-ATG4B antibody (ab70867)

This product has been referenced in:
  • Rothe K  et al. The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells. Blood 123:3622-34 (2014). WB ; Human . Read more (PubMed: 24755409) »

See 1 Publication for this product

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