Anti-ATM antibody [Y170] (ab32420)

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ab32420 has been referenced in 51 publications.

  • Göder A  et al. HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130. Nat Commun 9:764 (2018). PubMed: 29472538
  • Lung RW  et al. EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma. J Pathol 244:394-407 (2018). WB . PubMed: 29230817
  • Pancholi NJ & Weitzman MD Serotype-specific restriction of wild-type adenoviruses by the cellular Mre11-Rad50-Nbs1 complex. Virology 518:221-231 (2018). PubMed: 29547809
  • Pietrucha B  et al. Clinical and Biological Manifestation of RNF168 Deficiency in Two Polish Siblings. Front Immunol 8:1683 (2017). WB . PubMed: 29255463
  • Royba E  et al. Evaluation of ATM heterozygous mutations underlying individual differences in radiosensitivity using genome editing in human cultured cells. Sci Rep 7:5996 (2017). PubMed: 28729543
  • Wang L  et al. ATM Signaling Pathway Is Implicated in the SMYD3-mediated Proliferation and Migration of Gastric Cancer Cells. J Gastric Cancer 17:295-305 (2017). PubMed: 29302370
  • He H  et al. ATM mediates DAB2IP-deficient bladder cancer cell resistance to ionizing radiation through the p38MAPK and NF-?B signaling pathway. Mol Med Rep 16:1216-1222 (2017). PubMed: 28586028
  • Arnoult N  et al. Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN. Nature 549:548-552 (2017). PubMed: 28959974
  • Golia B  et al. ATM induces MacroD2 nuclear export upon DNA damage. Nucleic Acids Res 45:244-254 (2017). PubMed: 28069995
  • Zhang Y  et al. Cr(VI) induces premature senescence through ROS-mediated p53 pathway in L-02 hepatocytes. Sci Rep 6:34578 (2016). WB ; Human . PubMed: 27698449
  • Zhang H  et al. Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome. PLoS One 11:e0167454 (2016). WB, ICC/IF ; Human . PubMed: 27907109
  • Feng X  et al. Low Ki67/high ATM protein expression in malignant tumors predicts favorable prognosis in a retrospective study of early stage hormone receptor positive breast cancer. Oncotarget 7:85798-85812 (2016). IHC ; Human . PubMed: 27741524
  • Mertens B  et al. Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms. Oncotarget 7:47302-47318 (2016). WB . PubMed: 27331622
  • Villaruz LC  et al. ATM protein is deficient in over 40% of lung adenocarcinomas. Oncotarget 7:57714-57725 (2016). WB, IHC . PubMed: 27259260
  • Mandriota SJ  et al. Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism. Oncotarget 6:18558-76 (2015). IHC . PubMed: 26053094
  • Gao R  et al. Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3. PLoS Genet 11:e1004834 (2015). WB ; Human . PubMed: 25590633
  • Hu JL  et al. Abnormal Expression of DNA Double-Strand Breaks Related Genes, ATM and GammaH2AX, in Thyroid Carcinoma. Int J Endocrinol 2015:136810 (2015). IHC ; Human . PubMed: 25861265
  • Feng X  et al. Low ATM protein expression in malignant tumor as well as cancer-associated stroma are independent prognostic factors in a retrospective study of early-stage hormone-negative breast cancer. Breast Cancer Res 17:65 (2015). IHC ; Human . PubMed: 25935535
  • Tong AS  et al. ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres. Cell Rep 13:1633-46 (2015). WB . PubMed: 26586433
  • Ye P  et al. Intra-Tumoral Heterogeneity of HER2, FGFR2, cMET and ATM in Gastric Cancer: Optimizing Personalized Healthcare through Innovative Pathological and Statistical Analysis. PLoS One 10:e0143207 (2015). IHC-P ; Human . PubMed: 26587992
  • Mak KS  et al. Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor. Genome Biol 15:R58 (2014). WB ; Human . PubMed: 24946810
  • Abdel-Fatah TM  et al. Clinicopathological significance of ATM-Chk2 expression in sporadic breast cancers: a comprehensive analysis in large cohorts. Neoplasia 16:982-91 (2014). IHC ; Human . PubMed: 25425972
  • Lu H  et al. Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice. Cell Death Dis 5:e1226 (2014). WB ; Human . PubMed: 24832598
  • Kim H  et al. Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein expression is associated with a poorer prognosis. Clin Cancer Res 20:1865-72 (2014). IHC-P ; Human . PubMed: 24486587
  • Li WF  et al. WISP-1 contributes to fractionated irradiation-induced radioresistance in esophageal carcinoma cell lines and mice. PLoS One 9:e94751 (2014). PubMed: 24728101
  • Carlessi L  et al. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency. Cell Death Dis 5:e1342 (2014). WB ; Human . PubMed: 25032865
  • Shamanna RA  et al. RECQ helicase RECQL4 participates in non-homologous end joining and interacts with the Ku complex. Carcinogenesis 35:2415-24 (2014). WB ; Human . PubMed: 24942867
  • Balmer MT  et al. Doxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cells. Cancer Biol Ther 15:1000-12 (2014). PubMed: 24801380
  • Cesare AJ  et al. The telomere deprotection response is functionally distinct from the genomic DNA damage response. Mol Cell 51:141-55 (2013). Human . PubMed: 23850488
  • Kim HS  et al. Mutation at intronic repeats of the ataxia-telangiectasia mutated (ATM) gene and ATM protein loss in primary gastric cancer with microsatellite instability. PLoS One 8:e82769 (2013). IHC-P ; Human . PubMed: 24324828
  • Lundholm L  et al. Resistance to DNA-damaging treatment in non-small cell lung cancer tumor-initiating cells involves reduced DNA-PK/ATM activation and diminished cell cycle arrest. Cell Death Dis 4:e478 (2013). WB ; Human . PubMed: 23370278
  • Zhang ZZ  et al. Loss of BRCA1 expression leads to worse survival in patients with gastric carcinoma. World J Gastroenterol 19:1968-74 (2013). IHC-P ; Human . PubMed: 23569343
  • Gautam D & Bridge E The kinase activity of ataxia-telangiectasia mutated interferes with adenovirus E4 mutant DNA replication. J Virol 87:8687-96 (2013). PubMed: 23740981
  • Butin-Israeli V  et al. Regulation of nucleotide excision repair by nuclear lamin b1. PLoS One 8:e69169 (2013). WB ; Human . PubMed: 23894423
  • Köcher S  et al. ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks. Radiother Oncol N/A:N/A (2013). WB ; Human . PubMed: 23928469
  • Yajima H  et al. The complexity of DNA double strand breaks is a critical factor enhancing end-resection. DNA Repair (Amst) 12:936-46 (2013). WB ; Human . PubMed: 24041488
  • Hu S  et al. Nuclear survivin and its relationship to DNA damage repair genes in non-small cell lung cancer investigated using tissue array. PLoS One 8:e74161 (2013). IHC-P ; Human . PubMed: 24066112
  • Freund A  et al. Lamin B1 loss is a senescence-associated biomarker. Mol Biol Cell 23:2066-75 (2012). WB ; Human . PubMed: 22496421
  • Knappskog S  et al. Low expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer. Breast Cancer Res 14:R47 (2012). IHC-P ; Human . PubMed: 22420423
  • Mund A  et al. SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response. Nucleic Acids Res : (2012). Human . PubMed: 23034801
  • Ogiwara H & Kohno T CBP and p300 histone acetyltransferases contribute to homologous recombination by transcriptionally activating the BRCA1 and RAD51 genes. PLoS One 7:e52810 (2012). PubMed: 23285190
  • Beggs AD  et al. Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN. Oncotarget 3:1348-55 (2012). IHC . PubMed: 23154512
  • Geng L  et al. Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil. PLoS One 6:e28862 (2011). WB . PubMed: 22194930
  • Shkreta L  et al. The DNA Damage Response Pathway Regulates the Alternative Splicing of the Apoptotic Mediator Bcl-x. J Biol Chem 286:331-40 (2011). WB ; Human . PubMed: 20980256
  • Sánchez-Molina S  et al. Role for hACF1 in the G2/M damage checkpoint. Nucleic Acids Res : (2011). WB ; Human . PubMed: 21745822
  • Adeyemi RO  et al. Parvovirus minute virus of mice induces a DNA damage response that facilitates viral replication. PLoS Pathog 6:e1001141 (2010). PubMed: 20949077
  • Kadaja M  et al. Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses. PLoS Pathog 5:e1000397 (2009). ICC/IF ; Human . PubMed: 19390600
  • Jiang H  et al. The combined status of ATM and p53 link tumor development with therapeutic response. Genes Dev 23:1895-909 (2009). IHC-P ; Human . PubMed: 19608766
  • Rodier F  et al. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol 11:973-9 (2009). WB ; Human . PubMed: 19597488
  • Skaar JR  et al. INTS3 controls the hSSB1-mediated DNA damage response. J Cell Biol 187:25-32 (2009). WB ; Human . PubMed: 19786574
  • Biton S  et al. ATM-mediated response to DNA double strand breaks in human neurons derived from stem cells. DNA Repair (Amst) 6:128-34 (2007). Human . PubMed: 17178256


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