Anti-ATM (phospho S1981) antibody [EP1890Y] (ab81292)

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ab81292 has been referenced in 63 publications.

  • Kariolis MS  et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest 127:183-198 (2017). WB ; Human . PubMed: 27893463
  • Vancevska A  et al. The telomeric DNA damage response occurs in the absence of chromatin decompaction. Genes Dev 31:567-577 (2017). WB ; Human . PubMed: 28381410
  • Gallo A  et al. Oxytetracycline induces DNA damage and epigenetic changes: a possible risk for human and animal health? PeerJ 5:e3236 (2017). Human . PubMed: 28462039
  • Zhang H  et al. Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome. PLoS One 11:e0167454 (2016). WB, ICC/IF ; Human . PubMed: 27907109
  • García CP  et al. Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199. PLoS One 11:e0152607 (2016). ICC/IF ; Human . PubMed: 27030982
  • Capell BC  et al. MLL1 is essential for the senescence-associated secretory phenotype. Genes Dev 30:321-36 (2016). PubMed: 26833731
  • Cristini A  et al. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res 44:1161-78 (2016). WB ; Human . PubMed: 26578593
  • Althubiti M  et al. BTK Modulates p53 Activity to Enhance Apoptotic and Senescent Responses. Cancer Res 76:5405-14 (2016). PubMed: 27630139
  • Franz A  et al. Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression. Nat Commun 7:10612 (2016). PubMed: 26842564
  • Chou WC  et al. Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway. Carcinogenesis 36:832-40 (2015). PubMed: 26025911
  • Ray Chaudhuri A  et al. Poly(ADP-ribosyl) glycohydrolase prevents the accumulation of unusual replication structures during unperturbed S phase. Mol Cell Biol 35:856-65 (2015). PubMed: 25535335
  • Zeng YC  et al. Sodium glycididazole enhances the radiosensitivity of laryngeal cancer cells through downregulation of ATM signaling pathway. Tumour Biol N/A:N/A (2015). PubMed: 26586399
  • Sekimoto T  et al. Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication. Mol Cell Biol 35:699-715 (2015). PubMed: 25487575
  • Yu HP  et al. TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway. Sci Rep 5:9853 (2015). WB . PubMed: 25928429
  • Zellweger R  et al. Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells. J Cell Biol 208:563-79 (2015). WB ; Human . PubMed: 25733714
  • Khoronenkova SV & Dianov GL ATM prevents DSB formation by coordinating SSB repair and cell cycle progression. Proc Natl Acad Sci U S A 112:3997-4002 (2015). WB ; Human . PubMed: 25775545
  • Lu H  et al. Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice. Cell Death Dis 5:e1226 (2014). WB ; Human . PubMed: 24832598
  • García CP  et al. Topoisomerase I inhibitor, camptothecin, induces apoptogenic signaling in human embryonic stem cells. Stem Cell Res 12:400-14 (2014). ICC/IF ; Human . PubMed: 24380814
  • Hühn D  et al. miR-19, a component of the oncogenic miR-17~92 cluster, targets the DNA-end resection factor CtIP. Oncogene 0:N/A (2014). WB ; Human . PubMed: 25308476
  • Boichuk S  et al. Unbiased compound screening identifies unexpected drug sensitivities and novel treatment options for gastrointestinal stromal tumors. Cancer Res 74:1200-13 (2014). PubMed: 24385214
  • Chen W  et al. RIP1 maintains DNA integrity and cell proliferation by regulating PGC-1a-mediated mitochondrial oxidative phosphorylation and glycolysis. Cell Death Differ N/A:N/A (2014). PubMed: 24583643
  • Wang CY  et al. DNA-PK/Chk2 induces centrosome amplification during prolonged replication stress. Oncogene N/A:N/A (2014). PubMed: 24662822
  • Nikolaishvilli-Feinberg N  et al. Development of DNA damage response signaling biomarkers using automated, quantitative image analysis. J Histochem Cytochem 62:185-96 (2014). PubMed: 24309508
  • Gao M  et al. Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination. Cell Res 24:532-41 (2014). WB ; Human . PubMed: 24662483
  • Katsube T  et al. Most hydrogen peroxide-induced histone H2AX phosphorylation is mediated by ATR and is not dependent on DNA double-strand breaks. J Biochem N/A:N/A (2014). PubMed: 24682951
  • Guo K  et al. Development of a cell-based, high-throughput screening assay for ATM kinase inhibitors. J Biomol Screen 19:538-46 (2014). PubMed: 24464432
  • Münch S  et al. The tumor suppressor PML specifically accumulates at RPA/Rad51-containing DNA damage repair foci but is nonessential for DNA damage-induced fibroblast senescence. Mol Cell Biol 34:1733-46 (2014). PubMed: 24615016
  • Myung Park J  et al. Beclin 1 and UVRAG Confer Protection from Radiation-Induced DNA Damage and Maintain Centrosome Stability in Colorectal Cancer Cells. PLoS One 9:e100819 (2014). WB . PubMed: 24956373
  • Knobel PA  et al. USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism. Mol Cell Biol 34:2062-74 (2014). WB ; Human . PubMed: 24687851
  • Wang WT  et al. Differential response of normal and malignant urothelial cells to CHK1 and ATM inhibitors. Oncogene N/A:N/A (2014). PubMed: 25043304
  • Kotov IN  et al. Whole genome RNAi screens reveal a critical role of REV3 in coping with replication stress. Mol Oncol N/A:N/A (2014). PubMed: 25113059
  • Huang CY  et al. Extremely low-frequency electromagnetic fields cause G1 phase arrest through the activation of the ATM-Chk2-p21 pathway. PLoS One 9:e104732 (2014). WB ; Human . PubMed: 25111195
  • Hanada K  et al. Helicobacter pylori infection introduces DNA double-strand breaks in host cells. Infect Immun 82:4182-9 (2014). PubMed: 25069978
  • Anacker DC  et al. Productive replication of human papillomavirus 31 requires DNA repair factor Nbs1. J Virol 88:8528-44 (2014). WB ; Human . PubMed: 24850735
  • Huang CY  et al. Distinct epidermal keratinocytes respond to extremely low-frequency electromagnetic fields differently. PLoS One 9:e113424 (2014). WB ; Human . PubMed: 25409520
  • Sone K  et al. Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair. Nat Commun 5:5691 (2014). PubMed: 25487737
  • Fenton AL  et al. The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair. Nucleic Acids Res 41:4080-92 (2013). WB ; Human . PubMed: 23449221
  • Wu SY  et al. Development of modified siRNA molecules incorporating 5-fluoro-2'-deoxyuridine residues to enhance cytotoxicity. Nucleic Acids Res 41:4650-9 (2013). WB ; Human . PubMed: 23449220
  • Zhang D  et al. Sterigmatocystin-induced DNA damage triggers G2 arrest via an ATM/p53-related pathway in human gastric epithelium GES-1 cells in vitro. PLoS One 8:e65044 (2013). WB ; Human . PubMed: 23705030
  • Shiotani B  et al. Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1. Cell Rep 3:1651-62 (2013). PubMed: 23684611
  • Butin-Israeli V  et al. Regulation of nucleotide excision repair by nuclear lamin b1. PLoS One 8:e69169 (2013). WB ; Human . PubMed: 23894423
  • Zirkin S  et al. The PIM-2 kinase is an essential component of the ultraviolet damage response that acts upstream to E2F-1 and ATM. J Biol Chem 288:21770-83 (2013). WB ; Human . PubMed: 23760264
  • Tripathi DN  et al. Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1. Proc Natl Acad Sci U S A 110:E2950-7 (2013). WB ; Human . PubMed: 23878245
  • Köcher S  et al. ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks. Radiother Oncol N/A:N/A (2013). WB ; Human . PubMed: 23928469
  • Zhang J  et al. A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS. Nat Cell Biol 15:1186-96 (2013). PubMed: 23955302
  • Geuting V  et al. ATM release at resected double-strand breaks provides heterochromatin reconstitution to facilitate homologous recombination. PLoS Genet 9:e1003667 (2013). WB ; Human . PubMed: 23935532
  • Gamper AM  et al. ATR kinase activation in G1 phase facilitates the repair of ionizing radiation-induced DNA damage. Nucleic Acids Res N/A:N/A (2013). WB ; Human . PubMed: 24038466
  • Goldstein M  et al. Nucleolin mediates nucleosome disruption critical for DNA double-strand break repair. Proc Natl Acad Sci U S A 110:16874-9 (2013). WB ; Human . PubMed: 24082117
  • Yajima H  et al. The complexity of DNA double strand breaks is a critical factor enhancing end-resection. DNA Repair (Amst) 12:936-46 (2013). WB ; Human . PubMed: 24041488
  • Sakakibara N  et al. Brd4 Is Displaced from HPV Replication Factories as They Expand and Amplify Viral DNA. PLoS Pathog 9:e1003777 (2013). Human . PubMed: 24278023
  • Leung WH  et al. Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXR? activation. J Exp Med 210:2675-92 (2013). PubMed: 24190430
  • Kefala M  et al. Increased expression of phosphorylated NBS1, a key molecule of the DNA damage response machinery, is an adverse prognostic factor in patients with de novo myelodysplastic syndromes. Leuk Res 37:1576-82 (2013). Human . PubMed: 24054861
  • Zhou Y & Paull TT DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM). J Biol Chem 288:37112-25 (2013). Human . PubMed: 24220101
  • Cesare AJ  et al. The telomere deprotection response is functionally distinct from the genomic DNA damage response. Mol Cell 51:141-55 (2013). Human . PubMed: 23850488
  • Edwards TG  et al. Human papillomavirus episome stability is reduced by aphidicolin and controlled by DNA damage response pathways. J Virol 87:3979-89 (2013). WB ; Human . PubMed: 23365423
  • Horejší B  et al. Nuclear ?-tubulin associates with nucleoli and interacts with tumor suppressor protein C53. J Cell Physiol 227:367-82 (2012). PubMed: 21465471
  • Chen J & Herrup K Glutamine acts as a neuroprotectant against DNA damage, beta-amyloid and H2O2-induced stress. PLoS One 7:e33177 (2012). WB . PubMed: 22413000
  • Khalil HS  et al. Pharmacological inhibition of ATM by KU55933 stimulates ATM transcription. Exp Biol Med (Maywood) 237:622-34 (2012). PubMed: 22728709
  • Choi S  et al. CGK733 does not inhibit ATM or ATR kinase activity in H460 human lung cancer cells. DNA Repair (Amst) 10:1000-1 (2011). WB . PubMed: 21865098
  • Sakakibara N  et al. The papillomavirus e1 helicase activates a cellular DNA damage response in viral replication foci. J Virol 85:8981-95 (2011). ICC/IF ; Human . PubMed: 21734054
  • Neher TM  et al. Novel irreversible small molecule inhibitors of replication protein A display single-agent activity and synergize with cisplatin. Mol Cancer Ther 10:1796-806 (2011). WB ; Human . PubMed: 21846830
  • Gagou ME  et al. Suppression of Apoptosis by PIF1 Helicase in Human Tumor Cells. Cancer Res 71:4998-5008 (2011). WB ; Human . PubMed: 21616935
  • Chen J  et al. DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease. Mol Neurodegener 5:60 (2010). IHC-P ; Human . PubMed: 21172027


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