Anti-ATP13A2 antibody (ab43074)
Key features and details
- Rabbit polyclonal to ATP13A2
- Suitable for: IHC-Fr
- Reacts with: Rat
- Isotype: IgG
Overview
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Product name
Anti-ATP13A2 antibody
See all ATP13A2 primary antibodies -
Description
Rabbit polyclonal to ATP13A2 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Frmore details -
Species reactivity
Reacts with: Rat -
Immunogen
Synthetic peptide:
C-ELHRQEEAKQVLRYY
conjugated to KLH, corresponding to amino acids 147-161 of Mouse ATP13A2 -
Positive control
- Rat peripheral sensory ganglia.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7 -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab43074 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-Fr |
1/2000.
|
Notes |
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IHC-Fr
1/2000. |
Target
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Involvement in disease
Defects in ATP13A2 are the cause of Kufor-Rakeb syndrome (KRS) [MIM:606693]; also known as Parkinson disease type 9 (PARK9). KRS is a rare hereditary disease with juvenile onset. In addition to typical signs of Parkinson disease, affected individuals show symptoms of more widespread neurodegeneration, including dementia. -
Sequence similarities
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. -
Cellular localization
Membrane. - Information by UniProt
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Database links
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Alternative names
- AT132_HUMAN antibody
- Atp13a2 antibody
- ATPase type 13A2 antibody
see all
Images
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Ab43074 staining ATP13A2 by immunohistochemistry using frozen tissue.
The cryostat section of the rat spinal cord was incubated in ab43074 to the mouse ATPase protein at the dilution of 1:1000 overnight followed with a biotinylated secondary antibody and ABC kit. The section was developed in diaminobenzidine solution and enhanced in the presence of nickel sulphate. Cell bodies and nerve fibers in the trigeminal nerve are stained.
Datasheets and documents
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Datasheet download
References (0)
ab43074 has not yet been referenced specifically in any publications.