Overview

  • Product nameAnti-ATP2C1 antibody
    See all ATP2C1 primary antibodies
  • Description
    Rabbit polyclonal to ATP2C1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-919 of Human ATP2C1 (NP_055197.2).

  • Positive control
    • Mouse testis tissue lysate; HepG2 cell lysate; ATP2C1 transfected 293T cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab103587 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 101 kDa.

Target

  • FunctionThis magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium.
  • Tissue specificityFound in most tissues except colon, thymus, spleen and leukocytes. Most abundant in keratinocytes and kidney.
  • Involvement in diseaseDefects in ATP2C1 are the cause of Hailey-Hailey disease (HHD) [MIM:169600]; also known as benign familial pemphigus. HHD is an autosomal dominant disorder characterized by persistent blisters and suprabasal cell separation (acantholysis) of the epidermis, due to impaired keratinocyte adhesion. Patients lacking all isoforms except isoform 2 have HHD.
  • Sequence similaritiesBelongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
  • Cellular localizationGolgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1700121J11Rik antibody
    • AT2C1_HUMAN antibody
    • ATP dependent Ca(2+) pump PMR1 antibody
    • ATP-dependent Ca(2+) pump PMR1 antibody
    • ATP2C1 antibody
    • ATP2C1A antibody
    • ATPase 2C1 antibody
    • ATPase Ca(2+) sequestering antibody
    • ATPase Ca++ transporting type 2C member 1 antibody
    • AW061228 antibody
    • BCPM antibody
    • Calcium transporting ATPase type 2C member 1 antibody
    • Calcium-transporting ATPase type 2C member 1 antibody
    • D930003G21Rik antibody
    • HHD antibody
    • hSPCA1 antibody
    • HUSSY 28 antibody
    • KIAA1347 antibody
    • MGC58010 antibody
    • MGC93231 antibody
    • OTTHUMP00000216066 antibody
    • OTTHUMP00000216068 antibody
    • OTTHUMP00000216069 antibody
    • OTTHUMP00000216071 antibody
    • OTTHUMP00000216072 antibody
    • OTTHUMP00000216073 antibody
    • OTTHUMP00000216074 antibody
    • OTTHUMP00000216075 antibody
    • PMR1 antibody
    • PMR1, rat, homolog of antibody
    • PMR1L antibody
    • Secretory pathway Ca(2+) ATPase 1 antibody
    • Secretory pathway Ca(2+)-transporting ATPase antibody
    • Secretory pathway Ca2+/Mn2+ ATPase 1 antibody
    • SPCA antibody
    • SPCA1 antibody
    see all

Anti-ATP2C1 antibody images

  • Anti-ATP2C1 antibody (ab103587) at 1/500 dilution + Mouse testis tissue lysate at 50 µg

    Predicted band size : 101 kDa
  • Anti-ATP2C1 antibody (ab103587) at 1/500 dilution + HepG2 cell lysate at 50 µg

    Predicted band size : 101 kDa
  • All lanes : Anti-ATP2C1 antibody (ab103587) at 1/500 dilution

    Lane 1 : ATP2C1 transfected 293T cell line lysate
    Lane 2 : Non-transfected 293T cell line lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 101 kDa

References for Anti-ATP2C1 antibody (ab103587)

ab103587 has not yet been referenced specifically in any publications.

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