Anti-ATP5J antibody (ab65841)

Overview

• Product nameAnti-ATP5J antibody
  See all ATP5J primary antibodies
• Description
  Rabbit polyclonal to ATP5J
• Tested applicationsSuitable for: WB, IHC-Pmore details
• Species reactivity
  Reacts with: Mouse, Rat, Human
  
• Immunogen

  A synthetic peptide mapping at the middle region of human mature ATP5J, different from the related mouse sequence by two amino acids.

• Positive control
  • Mammary cancer tissue and rat liver tissue lysate.

Properties

• FormLyophilised:0.2ml of distilled water will yield a concentration of 500µg/ml.
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.02% Sodium Azide, 0.01% Thimerosal (merthiolate)
  Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
• Concentration information loading...
• PurityImmunogen affinity purified
• ClonalityPolyclonal
• IsotypeIgG
• Research areas
  • Tags & Cell Markers
  • Subcellular Markers
  • Organelles
  • Mitochondria

  • Signal Transduction
  • Metabolism
  • Mitochondrial

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitochondrial markers

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Oxidative phosphorylation
  • Complex V

  • Metabolism
  • Types of disease
  • Cancer

Associated products

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

Applications

Target

• FunctionMitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
• Sequence similaritiesBelongs to the eukaryotic ATPase subunit F6 family.
• Cellular localizationMitochondrion. Mitochondrion inner membrane.

• Target information above from: UniProt accession P18859 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 522 Human
  • Entrez Gene: 11957 Mouse
  • Entrez Gene: 94271 Rat
  • Omim: 603152 Human
  • SwissProt: P18859 Human
  • SwissProt: P97450 Mouse
  • SwissProt: P21571 Rat
  • Unigene: 246310 Human

  • Unigene: 353 Mouse
  • Unigene: 5790 Rat

  see all
• Alternative names
  • ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 antibody
  • ATP synthase-coupling factor 6, mitochondrial antibody
  • ATP synthase-coupling factor 6, mitochondrial antibody

  • ATP5 antibody
  • ATP5A antibody
  • ATP5J antibody
  • ATP5J_HUMAN antibody
  • ATPase subunit F6 antibody
  • ATPM antibody
  • CF6 antibody
  • F6 antibody

  see all