• Product nameAnti-ATP6V1B1 antibody
    See all ATP6V1B1 primary antibodies
  • Description
    Rabbit polyclonal to ATP6V1B1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig, Saccharomyces cerevisiae
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 395-444 (LMKSAIGEGM TRKDHGDVSN QLYACYAIGK DVQAMKAVVG EEALTSEDLL) of Human ATP6V1B1 (NP_001683).

  • Positive control
    • HeLa cell lysate



Our Abpromise guarantee covers the use of ab98991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 57 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionNon-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
  • Tissue specificityExpressed in the cochlea and endolymphatic sac.
  • Involvement in diseaseDefects in ATP6V1B1 are the cause of distal renal tubular acidosis with deafness (dRTA-D) [MIM:267300]. Inheritance is autosomal recessive. Patients with recessive dRTA are severely affected, presenting with either acute illness or growth failure at a young age, and bilateral sensorineural deafness. Other features include low serum K(+) due to renal potassium wasting, and elevated urinary calcium. If untreated, this acidosis may result in dissolution of bone, leading to osteomalacia and rickets. Renal deposition of calcium salts (nephrocalcinosis) and renal stone formation commonly occur.
  • Sequence similaritiesBelongs to the ATPase alpha/beta chains family.
  • DomainThe PDZ-binding motif mediates interactions with SLC9A3R1 and SCL4A7.
  • Cellular localizationEndomembrane system. Endomembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Atp6b1 antibody
    • ATP6V1B1 antibody
    • ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa, isoform 1 antibody
    • ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B, isoform 1 antibody
    • ATPase, H+ transporting, V1 subunit B, isoform 1 antibody
    • Endomembrane proton pump 58 kDa subunit antibody
    • H(+) transporting two sector ATPase 58kD subunit antibody
    • H+ ATPase beta 1 subunit antibody
    • kidney isoform antibody
    • Lysosomal 56/58kDa antibody
    • MGC32642 antibody
    • RTA1B antibody
    • V ATPase B1 subunit antibody
    • V type proton ATPase subunit B kidney isoform antibody
    • V type proton ATPase subunit B, kidney isoform antibody
    • V-ATPase subunit B 1 antibody
    • V-type proton ATPase subunit B antibody
    • Vacuolar proton pump 3 antibody
    • Vacuolar proton pump subunit 3 antibody
    • Vacuolar proton pump subunit B 1 antibody
    • VATB antibody
    • VATB1_HUMAN antibody
    • VMA2 antibody
    • Vpp 3 antibody
    • Vpp3 antibody
    see all

Anti-ATP6V1B1 antibody images

  • Anti-ATP6V1B1 antibody (ab98991) at 1 µg/ml + HeLa cell lysate at 10 µg

    Predicted band size : 57 kDa

References for Anti-ATP6V1B1 antibody (ab98991)

ab98991 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Loading amount 10 µg
Gel Running Conditions Reduced Denaturing
Sample Aedes aegypti (Mosquito) Tissue lysate - whole (Renal tubule)
Specification Renal tubule
Blocking step Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5%

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Submitted Oct 09 2014