Overview

  • Product nameAnti-ATPAF2 antibody
    See all ATPAF2 primary antibodies
  • Description
    Rabbit polyclonal to ATPAF2
  • SpecificityThis antibody detects endogenous levels of total ATPAF2 protein.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    A synthesized peptide derived from the internal region of human ATPAF2.

  • Positive control
    • Extracts from Jurkat cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab74235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/40000.
WB 1/500 - 1/1000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).

Target

  • RelevanceATPAF2 belongs to the ATP12 family. It may play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase). Defects in ATPAF2 are the cause of complex V mitochondrial respiratory chain ATPAF2 subunit deficiency (ATPAF2 deficiency) [MIM:604273]; also called ATP synthase deficiency or ATPase deficiency. ATPAF2 deficiency seems to be an early presenting disease in which lactic acidosis, dysmorphic features, and methyl glutaconic aciduria can be major clues in the diagnosis. Dysmorphic features include a large mouth, prominent nasal bridge, micrognathia, rocker-bottom feet and flexion contractures of the limbs associated with camptodactyly. Patients are hypertonic and have an enlarged liver, hypoplastic kidneys and elevated lactate levels in urine, plasma and cerebro spinal fluid (CSF).
  • Cellular localizationMitochondrion
  • Database links
  • Alternative names
    • ATP synthase mitochondrial F1 complex assembly factor 2 antibody
    • ATP12 antibody
    • ATP12 homolog antibody
    • ATP12p antibody
    • LP3663 antibody
    see all

Anti-ATPAF2 antibody images

  • All lanes : Anti-ATPAF2 antibody (ab74235) at 1/500 dilution

    Lane 1 : Extracts from Jurkat cells
    Lane 2 : Extracts from Jurkat cells plus 5µg immunizing peptide

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 33 kDa
    Observed band size : 33 kDa

References for Anti-ATPAF2 antibody (ab74235)

ab74235 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"