Overview

  • Product nameAnti-ATRIP antibody
    See all ATRIP primary antibodies
  • Description
    Rabbit polyclonal to ATRIP
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee
  • Immunogen

    Synthetic peptide corresponding to a region between residue 100 to 150 of Human ATRIP (NP_569055.1)

  • Positive control
    • Human breast carcinoma and prostate carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab90614 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500. Perform enzymatic antigen retrieval before commencing with IHC staining protocol. Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
    Likely to work with frozen sections.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionRequired for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
    • Tissue specificityUbiquitous.
    • Sequence similaritiesBelongs to the ATRIP family.
    • DomainThe EEXXXDDL motif is required for the interaction with catalytic subunit PRKDC and its recruitment to sites of DNA damage.
    • Post-translational
      modifications
      Phosphorylated by ATR.
    • Cellular localizationNucleus. Redistributes to discrete nuclear foci upon DNA damage.
    • Information by UniProt
    • Database links
    • Alternative names
      • AGS1 antibody
      • ATIP antibody
      • ATM and Rad3 related interacting protein antibody
      • ATM and Rad3-related-interacting protein antibody
      • ATR interacting protein antibody
      • ATR-interacting protein antibody
      • Atrip antibody
      • ATRIP_HUMAN antibody
      • DKFZp762J2115 antibody
      • FLJ12343 antibody
      • MGC20625 antibody
      • MGC21482 antibody
      • MGC26740 antibody
      see all

    Anti-ATRIP antibody images

    • Immunohistochemical analysis of Human ATRIP in formalin-fixed paraffin-embedded human prostate carcinoma tissue using ab90614 at a dilution of 1/250

    References for Anti-ATRIP antibody (ab90614)

    ab90614 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab90614.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"