Overview

  • Product nameAnti-ATXN10 antibody
    See all ATXN10 primary antibodies
  • Description
    Rabbit polyclonal to ATXN10
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Guinea pig, Cow, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 8-57 (PARLSGVMVP APIQDLEALR ALTALFKEQR NRETAPRTIF QRVLDILKKS) of Human ATXN10 (NM_013236).

  • Positive control
    • 293T cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferConstituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab116528 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 53 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionNecessary for the survival of cerebellar neurons (By similarity). Induces neuritogenesis by activating the Ras-MAP kinase pathway (By similarity). May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
  • Tissue specificityExpressed in the central nervous system.
  • Involvement in diseaseDefects in ATXN10 are the cause of spinocerebellar ataxia type 10 (SCA10) [MIM:603516]. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA10 is an autosomal dominant cerebellar ataxia (ADCA).
  • Sequence similaritiesBelongs to the ataxin-10 family.
  • Cellular localizationCytoplasm > perinuclear region.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ataxin 10 antibody
    • Ataxin-10 antibody
    • ATX10_HUMAN antibody
    • Atxn10 antibody
    • Brain protein E46 homolog antibody
    • E46L antibody
    • FLJ37990 antibody
    • HUMEEP antibody
    • Like mouse brain protein E46 antibody
    • OTTHUMP00000197383 antibody
    • SCA10 antibody
    • Spinocerebellar ataxia 10 antibody
    • Spinocerebellar ataxia type 10 protein antibody
    see all

Anti-ATXN10 antibody images

  • Anti-ATXN10 antibody (ab116528) at 1 µg/ml + 293T cell lysate at 10 µg

    Predicted band size : 53 kDa

References for Anti-ATXN10 antibody (ab116528)

ab116528 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"