Anti-Avian Influenza A Nonstructural 1 antibody (ab45417)

Overview

  • Product name
    Anti-Avian Influenza A Nonstructural 1 antibody
  • Description
    Rabbit polyclonal to Avian Influenza A Nonstructural 1
  • Specificity
    This antibody is specific for Avian Influenza A Nonstructural 1.
  • Tested applications
    Suitable for: ELISAmore details
  • Species reactivity
    Avian Influenza A
  • Immunogen

    A synthetic peptide corresponding to 14 amino acids at the carboxy terminus of the Avian Influenza A Nonstructural 1 protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab45417 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 1 µg/ml. to detect 10 ng of free peptide.

Target

  • Relevance
    Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor (CPSF4) and the poly(A)-binding protein 2 (PABPN1). This results in the accumulation of unprocessed 3' end pre-mRNAs which can't be exported from the nucleus.
  • Cellular localization
    In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, and a fraction of NS1 is exported in the cytoplasm
  • Alternative names
    • Nonstructural protein 1 antibody
    • NS1 antibody

References

ab45417 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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