General notesab94145 is a 293T cell transfected lysate in which Human Axl has been transiently over-expressed using a pCMV-Axl plasmid. The lysate is provided in 1 x Sample Buffer.
Note: For more details about how the transfected lysate was prepared view preparation notes
BackgroundFunction: May function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, seems to function as a cell entry factor.
Tissue specificity: Highly expressed in metastatic colon tumors. Expressed in primary colon tumors. Weakly expressed in normal colon tissue.
Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
Contains 2 fibronectin type-III domains.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain.