Anti-Azurocidin antibody (Biotin) (ab51508)

Overview

  • Product nameAnti-Azurocidin antibody (Biotin)
    See all Azurocidin primary antibodies
  • Description
    Rabbit polyclonal to Azurocidin (Biotin)
  • ConjugationBiotin
  • Tested applicationsSuitable for: ELISA, WB, RIAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human Azurocidin

Properties

Applications

Our Abpromise guarantee covers the use of ab51508 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 28 kDa.
RIA Use at an assay dependent concentration.

Target

  • FunctionThis is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G.
  • Sequence similaritiesBelongs to the peptidase S1 family. Elastase subfamily.
    Contains 1 peptidase S1 domain.
  • Cellular localizationCytoplasmic granule. Cytoplasmic granules of neutrophils.
  • Information by UniProt
  • Database links
  • Alternative names
    • Azu 1 antibody
    • AZU1 antibody
    • Azurocidin antibody
    • CAP37 antibody
    • CAP7_HUMAN antibody
    • Cationic antimicrobial protein 37 antibody
    • Cationic antimicrobial protein CAP37 antibody
    • HBP antibody
    • Heparin binding protein antibody
    • Heparin-binding protein antibody
    • HUMAZUR antibody
    • Neutrophil azurocidin antibody
    see all

References for Anti-Azurocidin antibody (Biotin) (ab51508)

ab51508 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application ELISA
Sample Human Cell (293T Lysate (mock or AZU1-Flag transfection))
Specification 293T Lysate (mock or AZU1-Flag transfection)
Blocking step BSA as blocking agent for 30 minute(s) · Concentration: 1% · Temperature: 25°C
Type Sandwich (Detection)
Username

Abcam user community

Verified customer

Submitted Oct 17 2016

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"