Anti-B Cell antibody [BB6-10A10] (FITC) (ab24890)

Overview

  • Product name
    Anti-B Cell antibody [BB6-10A10] (FITC)
    See all B Cell primary antibodies
  • Description
    Mouse monoclonal [BB6-10A10] to B Cell (FITC)
  • Host species
    Mouse
  • Conjugation
    FITC. Ex: 493nm, Em: 528nm
  • Specificity
    The specificity of this antibody is indeterminate. It stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues: 11-15% in peripheral blood; 22-23% in mesenteric lymph nodes; 79-87% in ileal Peyer's patches (ILPP); 6-17 in spleen; and 0% in thymus. While identification of the antigen(s) that are found predominantly on ILPP B cells and which are recognized by this is speculative, the antibody appears to react with an immature population of B cells in the follicles of ILPPs and with a subpopulation of sIg low B cells in lymph nodes.
  • Tested applications
    Suitable for: Flow Cyt, IHC-Frmore details
  • Species reactivity
    Reacts with: Pig
  • Immunogen

    The details of the immunogen for this antibody are not available.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C.
  • Storage buffer
    Preservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Purified IgM
  • Clonality
    Monoclonal
  • Clone number
    BB6-10A10
  • Isotype
    IgM
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab24890 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 1µg for 106 cells.

ab91546 - Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody.

IHC-Fr Use at an assay dependent concentration.

Acetone fixed.

Target

  • Relevance
    B cells are lymphocytes that are produced in the bone marrow and require bone marrow stromal cells and their cytokines for maturation. During its development, each B cell becomes genetically programmed through a series of gene splicing reactions to produce an antibody molecule with a unique specificity.

References

ab24890 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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