Anti-B7H4 antibody [MIH43] (FITC) (ab110222)

Overview

  • Product nameAnti-B7H4 antibody [MIH43] (FITC)
    See all B7H4 primary antibodies
  • Description
    Mouse monoclonal [MIH43] to B7H4 (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue/ cell preparation (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab110222 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/1 - 1/5. Use 10µl of the suggested working dilution to label 1x104 cells in 100µl.



ab91356-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • FunctionNegatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
  • Tissue specificityOverexpressed in breast, ovarian, endometrial, renal cell (RCC) and non-small-cell lung cancers (NSCLC). Expressed on activated T- and B-cells, monocytes and dendritic cells, but not expressed in most normal tissues (at protein level). Widely expressed, including in kidney, liver, lung, ovary, placenta, spleen and testis.
  • Sequence similaritiesBelongs to the immunoglobulin superfamily. BTN/MOG family.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationCell membrane. Expressed at the cell surface. A soluble form has also been detected.
  • Information by UniProt
  • Database links
  • Alternative names
    • B7 family member, H4 antibody
    • B7 H4 antibody
    • B7 homolog 4 antibody
    • B7 superfamily member 1 antibody
    • B7 superfamily, member 1 antibody
    • B7-H4 antibody
    • B7h.5 antibody
    • B7h4 antibody
    • B7S1 antibody
    • B7x antibody
    • BC032925 antibody
    • Immune costimulatory protein B7-H4 antibody
    • Immune costimulatory protein B7H4 antibody
    • MGC41287 antibody
    • PRO1291 antibody
    • Protein B7S1 antibody
    • RP11 229A19.4 antibody
    • T cell costimulatory molecule B7x antibody
    • T-cell costimulatory molecule B7x antibody
    • V set domain-containing T cell activation inhibitor 1 antibody
    • V-set domain-containing T-cell activation inhibitor 1 antibody
    • VCTN1 antibody
    • Vtcn1 antibody
    • VTCN1_HUMAN antibody
    see all

Anti-B7H4 antibody [MIH43] (FITC) images

  • ab110222 staining B7H4 in peripheral human blood monocytes by Flow Cytometry.

References for Anti-B7H4 antibody [MIH43] (FITC) (ab110222)

ab110222 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab110222.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"