Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-KQNGLQTTEAKRDAK
    • Amino acids
      135 to 149

Specifications

Our Abpromise guarantee covers the use of ab45827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • BAALC
    • BAALC_HUMAN
    • Brain and acute leukemia cytoplasmic
    • Brain and acute leukemia cytoplasmic protein
    • FLJ12015
    see all
  • Function
    May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A.
  • Tissue specificity
    Expressed by neural and hematopoietic cells. Expression is found both in normal early progenitor cells and in the most immature type of blasts in acute leukemia but not in mature hematopoietic cells. Isoform 2 and isoform 6 are expressed in the brain. Isoform 2 shows a low expression in neuroectoderm-derived tissues such as adrenal gland and no expression in bone marrow, peripheral blood lymphocytes or lymph nodes, or in tumors or cancer cell lines of nonneural tissue origin.
  • Post-translational
    modifications
    Palmitoylation and myristoylation target the protein to the lipid rafts.
  • Cellular localization
    Cytoplasm. Membrane. Postsynaptic lipid rafts.
  • Information by UniProt

References

ab45827 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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