Anti-BRAT1 antibody (ab84362)
Key features and details
- Rabbit polyclonal to BRAT1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-BRAT1 antibody
See all BRAT1 primary antibodies -
Description
Rabbit polyclonal to BRAT1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan -
Immunogen
Synthetic peptide corresponding to Human BRAT1 aa 775-821 (C terminal).
Database link: NP_689956.1 -
Positive control
- Human metastatic lymph node; Human lung non small cell cancer
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Purified using an epitope specific to BRAT1 immobilized on solid support. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab84362 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
1/100 - 1/500.
Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. |
Notes |
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IHC-P
1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. |
Target
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Function
Required for activation of ATM following ionizing radiation. May act by regulating dephosphorylation of ATM. -
Tissue specificity
Ubiquitously expressed. -
Sequence similarities
Contains 2 HEAT repeats. -
Cellular localization
Nucleus. Present at double strand breaks (DSBs) following ionizing radiation treatment. - Information by UniProt
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Database links
- Entrez Gene: 221927 Human
- Omim: 614506 Human
- SwissProt: Q6PJG6 Human
- Unigene: 520623 Human
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Alternative names
- BAAT 1 antibody
- BAAT1 antibody
- BRAT 1 antibody
see all
Images
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Detection of Human BRAT1 in formalin-fixed paraffin-embedded section of Human metastatic lymph node by Immunohistochemistry using ab84362 at a dilution of 1/250. Detection was performed by DAB staining using anti-Rabbit IHC antibody at a dilution of 1/100.
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Detection of Human BRAT1 in formalin-fixed paraffin-embedded section of Human lung non-small cell cancer by Immunohistochemistry using ab84362 at a dilution of 1/250. Detection was performed by DAB staining using anti-Rabbit IHC antibody at a dilution of 1/100.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab84362 has not yet been referenced specifically in any publications.