Overview

  • Product nameAnti-Baboon antibody
    See all Baboon primary antibodies
  • Description
    Rabbit polyclonal to Baboon
  • SpecificityThe antibody is unique to Baboon protein.
  • Tested applicationsSuitable for: IP, WBmore details
  • Species reactivity
    Reacts with: Drosophila melanogaster
  • Immunogen

    Synthetic peptide:

    QPDPSIEEMKKVVCIEKCRPN

    , corresponding to amino acids 552 to 572 of Baboon. The was generated against a peptide sequence near the C terminal end of the protein. The peptides was amidated for conjugation.

  • Positive control
    • Drosophila melanogaster extracts.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified against immobilized antigen based affinity chromatography which yielded epitope specific antibodies.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab14682 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP
WB
  • Application notesIP: 1/200.
    WB: 1/500.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceTransmembrane receptor Patched regulates several developmental processes in both invertebrates and vertebrates. In higher vertebrates the patched (Ptc) also acts as a tumor suppressor. The patched receptor signaling involves negatively regulating a GPCR, smoothened. The binding Hedgehog ligand to Ptc removes the negative interaction of Ptc, and allows the signaling by smoothened. It has been shown that during head morphogenesis in D. melanogaster, Ptc positively interacts with smoothened, which leads to stimulation of Activin type 1 receptor Baboon, and activation of cell proliferation in the eye antennal disc. The expression of activated Baboon in the Ptc domain in Ptc mutant background completely abolish the head developmental defects.
    • Database links
      • Alternative names
        • ATR1 antibody
        • AtrI antibody
        • Bab antibody
        • Babo antibody
        • G protein coupled receptor kinase 3 antibody
        • STKE antibody
        see all

      References for Anti-Baboon antibody (ab14682)

      ab14682 has not yet been referenced specifically in any publications.

      Product Wall

      Application IHC - Wholemount
      Sample Fruit fly (Drosophila melanogaster) Tissue (Brain)
      Specification Brain
      Username

      Abcam user community

      Verified customer

      Submitted Aug 20 2015

      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"