Anti-Bacillus anthracis protective antigen antibody [BAP0101] (ab1988)

Overview

  • Product nameAnti-Bacillus anthracis protective antigen antibody [BAP0101]
    See all Bacillus anthracis protective antigen primary antibodies
  • Description
    Mouse monoclonal [BAP0101] to Bacillus anthracis protective antigen
  • SpecificityThis antibody does not cross-react with lethal factor antigen of B. antracis, Y.Pestis, F. Tularensis, and Toxoplasma gondii.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Immunogen

    Highly purified protective antigen of Bacillus anthracis.

  • General notesConcentration varies from lot to lot and can be provided on request.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesPurity is tested by electrophoresis.
  • ClonalityMonoclonal
  • Clone numberBAP0101
  • MyelomaSp2/0
  • IsotypeIgG2b
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab1988 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notesELISA: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Recognizes both 83K and truncated 63K forms of PA.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceAnthrax toxins are composed of three distinct proteins, a protective antigen (PA), a lethal factor (LF) and an edema factor (EF). None of these proteins are toxic by themselves and several studies indicate that the anthrax toxin has the familiar A-B enzymatic binding structure, with PA acting as the binding domain and EF and/or LF acting as the active fragments.
    • Cellular localizationSecreted
    • Alternative names
      • PA antibody
      • PA83 antibody
      • pag antibody
      • PagA antibody
      • Protective antigen antibody
      see all

    References for Anti-Bacillus anthracis protective antigen antibody [BAP0101] (ab1988)

    This product has been referenced in:
    • Schumacher WC  et al. Identification and characterization of Bacillus anthracis spores by multiparameter flow cytometry. Appl Environ Microbiol 74:5220-3 (2008). Read more (PubMed: 18586967) »

    See 1 Publication for this product

    Product Wall

    Thank you for your enquiry. We unfortunately do not have information on the exact domains that these antibodies bind to. For clones BAP0101-BAP0106 all recognize both full size (83kDa) and cleaved (63kDa)protective antigen. The antibodies can be di...

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    All clones recognize both forms of PA. If you have any more questions, please contact us again.

    Thank you for your enquiry. Regarding the antibodies that you are interested in, all clones are directed against different epitopes of protective antigen. They recognize both 83 K and truncated 63 K forms of protective antigen. Unfortunately we have no...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"