Validated using a knockout cell line

Anti-Bad antibody [Y208] (ab32445)

Publishing research using ab32445? Please let us know so that we can cite the reference in this datasheet.

ab32445 has been referenced in 29 publications.

  • Martínez-François JR  et al. BAD and KATPchannels regulate neuron excitability and epileptiform activity. Elife 7:N/A (2018). PubMed: 29368690
  • You S  et al. Tunicamycin inhibits colon carcinoma growth and aggressiveness via modulation of the ERK-JNK-mediated AKT/mTOR signaling pathway. Mol Med Rep 17:4203-4212 (2018). PubMed: 29344654
  • Wang Q  et al. Resistant starch prevents tumorigenesis of dimethylhydrazine-induced colon tumors via regulation of an ER stress-mediated mitochondrial apoptosis pathway. Int J Mol Med 41:1887-1898 (2018). PubMed: 29393371
  • Wang MS  et al. Iron oxide magnetic nanoparticles combined with actein suppress non-small-cell lung cancer growth in a p53-dependent manner. Int J Nanomedicine 12:7627-7651 (2017). WB ; Human . PubMed: 29089760
  • Beffagna G  et al. Circulating Cell-Free DNA in Dogs with Mammary Tumors: Short and Long Fragments and Integrity Index. PLoS One 12:e0169454 (2017). PubMed: 28081183
  • Liu Y  et al. Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice. Int J Mol Med 40:357-366 (2017). PubMed: 28656204
  • Xu G & Dang C CMTM5 is downregulated and suppresses tumour growth in hepatocellular carcinoma through regulating PI3K-AKT signalling. Cancer Cell Int 17:113 (2017). PubMed: 29213215
  • Wu Z  et al. Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget 8:71954-71964 (2017). PubMed: 29069760
  • Luo J  et al. Ursolic acid inhibits breast cancer growth by inhibiting proliferation, inducing autophagy and apoptosis, and suppressing inflammatory responses via the PI3K/AKT and NF-?B signaling pathwaysin vitro. Exp Ther Med 14:3623-3631 (2017). PubMed: 29042957
  • Kaul Z & Chakrabarti O Tumor susceptibility gene 101 regulates predisposition to apoptosis via ESCRT machinery accessory proteins. Mol Biol Cell 28:2106-2122 (2017). PubMed: 28539405
  • You Y  et al. MicroRNA-216b-5p Functions as a Tumor-suppressive RNA by Targeting TPT1 in Pancreatic Cancer Cells. J Cancer 8:2854-2865 (2017). WB . PubMed: 28928875
  • Li Y  et al. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study. PLoS Med 13:e1002200 (2016). WB ; Human . PubMed: 27997540
  • Yang Z  et al. Phosphorylation and inactivation of PTEN at residues Ser380/Thr382/383 induced by Helicobacter pylori promotes gastric epithelial cell survival through PI3K/Akt pathway. Oncotarget 6:31916-26 (2015). IHC-P ; Human . PubMed: 26376616
  • Eng JW  et al. Housing temperature-induced stress drives therapeutic resistance in murine tumour models through ß2-adrenergic receptor activation. Nat Commun 6:6426 (2015). WB . PubMed: 25756236
  • Chen Z  et al. Rictor/mTORC2 pathway in oocytes regulates folliculogenesis, and its inactivation causes premature ovarian failure. J Biol Chem 290:6387-96 (2015). PubMed: 25564616
  • Sun Y  et al. Up-regulation of eEF1A2 promotes proliferation and inhibits apoptosis in prostate cancer. Biochem Biophys Res Commun 450:1-6 (2014). WB ; Human . PubMed: 24853801
  • Sachewsky N  et al. Cyclosporin A enhances neural precursor cell survival in mice through a calcineurin-independent pathway. Dis Model Mech 7:953-61 (2014). WB ; Mouse . PubMed: 25056698
  • Su CC  et al. 13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression. Mar Drugs 12:5295-315 (2014). PubMed: 25342459
  • Brennan GP  et al. Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. PLoS One 8:e54491 (2013). WB ; Mouse . PubMed: 23359526
  • Narlik-Grassow M  et al. Conditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasia. PLoS One 8:e60277 (2013). WB ; Mouse . PubMed: 23565217
  • Burns SS  et al. Histone deacetylase inhibitor AR-42 differentially affects cell-cycle transit in meningeal and meningioma cells, potently inhibiting NF2-deficient meningioma growth. Cancer Res 73:792-803 (2013). WB . PubMed: 23151902
  • Dettwiler M  et al. Immunohistochemical Expression Study of Proapoptotic BH3-Only Protein Bad in Canine Nonneoplastic Tissues and Canine Lymphomas. Vet Pathol N/A:N/A (2013). WB, IHC-P ; Dog . PubMed: 23417166
  • Schlossmacher G  et al. Glucocorticoid receptor-mediated apoptosis in small-cell lung cancer requires interaction with BCL2. Endocr Relat Cancer 20:785-95 (2013). PubMed: 24036132
  • Chile T  et al. HOXB7 mRNA is overexpressed in pancreatic ductal adenocarcinomas and its knockdown induces cell cycle arrest and apoptosis. BMC Cancer 13:451 (2013). Flow Cyt ; Human . PubMed: 24088503
  • Zhang H  et al. Mcl-1 is critical for survival in a subgroup of non-small-cell lung cancer cell lines. Oncogene 30:1963-8 (2011). WB ; Human . PubMed: 21132008
  • Coutinho-Camillo CM  et al. Expression of Bcl-2 family proteins and association with clinicopathological characteristics of oral squamous cell carcinoma. Histopathology 57:304-16 (2010). IHC ; Human . PubMed: 20716171
  • Shah OJ  et al. Bcl-XL represents a druggable molecular vulnerability during aurora B inhibitor-mediated polyploidization. Proc Natl Acad Sci U S A 107:12634-9 (2010). PubMed: 20616035
  • Maes OC  et al. Stepwise up-regulation of microRNA expression levels from replicating to reversible and irreversible growth arrest states in WI-38 human fibroblasts. J Cell Physiol 221:109-19 (2009). PubMed: 19475566
  • Miyawaki T  et al. Ischemic preconditioning blocks BAD translocation, Bcl-xL cleavage, and large channel activity in mitochondria of postischemic hippocampal neurons. Proc Natl Acad Sci U S A 105:4892-7 (2008). PubMed: 18347331


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