Overview

  • Product nameAnti-BAFF Receptor antibody
    See all BAFF Receptor primary antibodies
  • Description
    Rabbit polyclonal to BAFF Receptor
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (Human). The peptide sequence is identical between human and mouse origin.

  • Positive control
    • WB: Human, Mouse or Rat spleen tissue lysate. IHC: human lymphoid tissue (see review), human tonsil tissue
  • General notesStable for one year.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C. Avoid freeze / thaw cycle. Stable for 12 months at -20°C.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesBAFF Receptor Antibody is affinity chromatography purified via peptide column.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab5965 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2 - 5 µg/ml. Predicted molecular weight: 19 kDa.Can be blocked with Human BAFF Receptor peptide (ab6086).
IHC-P 1/1000 - 1/2000.

Target

  • FunctionB-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
  • Tissue specificityHighly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes.
  • Involvement in diseaseDefects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) [MIM:613494]; also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
  • Sequence similaritiesContains 1 TNFR-Cys repeat.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • B cell activating factor receptor antibody
    • B-cell-activating factor receptor antibody
    • BAFF R antibody
    • BAFF receptor antibody
    • BAFF-R antibody
    • BAFFR antibody
    • BLyS receptor 3 antibody
    • BlySR3 antibody
    • BR 3 antibody
    • BR3 antibody
    • BROMIX antibody
    • CD 268 antibody
    • CD268 antibody
    • CD268 antigen antibody
    • CVID4 antibody
    • MGC138235 antibody
    • OTTHUMP00000028746 antibody
    • Prolixin antibody
    • TNFRSF 13C antibody
    • Tnfrsf13c antibody
    • TR13C_HUMAN antibody
    • Tumor necrosis factor receptor subunit member 13C antibody
    • Tumor necrosis factor receptor superfamily member 13C antibody
    see all

Anti-BAFF Receptor antibody images



  • Predicted band size : 19 kDa

    Western blot analysis of BAFF Receptor in human (H), mouse (M), and rat (R) spleen tissue lysates with ab5965 at 5 µg/ml.

    Western blot analysis of BAFF Receptor in human (H), mouse (M), and rat (R) spleen tissue lysates with ab5965 at 5 µg/ml.
  • Immunohistochemistry (formalin-fixed paraffin-embedded) of BAFF Receptor in human tonsil tissue with ab5965 at 5 ug/ml.

References for Anti-BAFF Receptor antibody (ab5965)

This product has been referenced in:
  • Price JV  et al. Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus. J Clin Invest 123:5135-45 (2013). Read more (PubMed: 24270423) »
  • Hildebrand JM  et al. A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling. J Exp Med 207:2569-79 (2010). WB ; Human . Read more (PubMed: 21041452) »

See all 3 Publications for this product

Product Wall

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Vielen Dank für Ihren Anruf und dafür, dass Sie sich die Zeit genommen haben, unseren Fragebogen auszufüllen.

Ihr Western blot-Protokoll ist absolut in Ordnung. Auch wenn unser Labor Antikörper routinemäβig 5% BS...

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Vielen Dank für Ihren Anruf.

Es tut mir leid zu hören, dass Sie Probleme mit diesem BAFF Receptor-Antikörper haben.

Wie besprochen habe ich unseren Fragebogen als Word-Dokument an diese E-Mail angehängt. Durch da...

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Thank you for contacting us. Because we carry over 70,000 products, it isn't feasible for us to keep small sample sizes of our products.

We are happy to reassure our customers that all of our products are covered by our Abpromise, which guar...

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Thank you for your enquiry. You are correct, there is a discrepancy on this antibody datasheet. Please let me apologise for this discrepancy. This antibody is in fact sourced from an external originator. The information that we have been provided w...

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Thank you for your email. The peptide sequence used to generate this antibody is as follows: GSTELVTTKTAGPEQ (amino acids 169-183 of Human Baff receptor). This peptide is also available - Abca, catalog number ab6086. If you have any additional questi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"