Recombinant
RabMAb

Anti-BAFF Receptor antibody [EPR10914] (ab168389)

Overview

  • Product name
    Anti-BAFF Receptor antibody [EPR10914]
    See all BAFF Receptor primary antibodies
  • Description
    Rabbit monoclonal [EPR10914] to BAFF Receptor
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, ICC/IFmore details
    Unsuitable for: Flow Cyt,IP or WB
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to residues in Human BAFF Receptor (UniProt: Q96RJ3).

  • Positive control
    • Human colon and tonsil tissues; Raji cells.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 50% Glycerol, 0.05% BSA
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR10914
  • Isotype
    IgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab168389 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF 1/50 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt,IP or WB.
  • Target

    • Function
      B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
    • Tissue specificity
      Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes.
    • Involvement in disease
      Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) [MIM:613494]; also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
    • Sequence similarities
      Contains 1 TNFR-Cys repeat.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • B cell activating factor receptor antibody
      • B-cell-activating factor receptor antibody
      • BAFF R antibody
      • BAFF receptor antibody
      • BAFF-R antibody
      • BAFFR antibody
      • BLyS receptor 3 antibody
      • BlySR3 antibody
      • BR 3 antibody
      • BR3 antibody
      • BROMIX antibody
      • CD 268 antibody
      • CD268 antibody
      • CD268 antigen antibody
      • CVID4 antibody
      • MGC138235 antibody
      • OTTHUMP00000028746 antibody
      • Prolixin antibody
      • TNFRSF 13C antibody
      • Tnfrsf13c antibody
      • TR13C_HUMAN antibody
      • Tumor necrosis factor receptor subunit member 13C antibody
      • Tumor necrosis factor receptor superfamily member 13C antibody
      see all

    Images

    • Immunohistochemical analysis of paraffin-embedded Human colon tissue labeling BAFF Receptor with ab168389 at 1/250 dilution.
    • Immunohistochemical analysis of paraffin-embedded Human tonsil tissue labeling BAFF Receptor with ab168389 at 1/250 dilution.
    • Immunofluorescent analysis of Raji cells labeling BAFF Receptor with ab168389 at 1/50 dilution.

    References

    ab168389 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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