Overview

  • Product nameAnti-Bag5 antibodySee all Bag5 primary antibodies ...
  • Description
    Mouse monoclonal to Bag5
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-448 of Human Bag5

Properties

Applications

Our Abpromise guarantee covers the use of ab56738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.
    • Sequence similaritiesContains 5 BAG domains.
    • DomainThe fifth BAG domain is responsible for the interaction with HSP70 nucleotide-binding domain.
    • Target information above from: UniProt accession Q9UL15 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
    • Alternative names
      • BAG family molecular chaperone regulator 5 antibody
      • BAG-5 antibody
      • BAG5 antibody
      • BAG5_HUMAN antibody
      • Bcl-2-associated athanogene 5 antibody
      • BCL2 associated athanogene 5 antibody
      • KIAA0873 antibody
      see all

    Anti-Bag5 antibody images



    • Predicted band size : 51 kDa
      Bag5 antibody (ab56738) at 1ug/lane + Jurkat cell lysate at 25ug/lane.

    References for Anti-Bag5 antibody (ab56738)

    This product has been referenced in:
    • Boiani M  et al. The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737. J Biol Chem 288:6980-90 (2013). WB ; Human . Read more (PubMed: 23341456) »
    • Gong C & Maquat LE lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements. Nature 470:284-8 (2011). WB ; Human . Read more (PubMed: 21307942) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"