Anti-BAI1 associated protein 2 isoform 3 antibody (ab791)

Overview

  • Product nameAnti-BAI1 associated protein 2 isoform 3 antibody
  • Description
    Goat polyclonal to BAI1 associated protein 2 isoform 3
  • SpecificityThis antibody will only recognise isoform 3 of the three reported isoforms.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Dog
  • Immunogen

    Synthetic peptide: SMSSADVEVARF, corresponding to C terminal amino acids 509-520 of Human BAI1 associated protein 2 isoform 3.

  • Positive control
    • HeLa cell lysates
  • General notes


    Brain-specific angiogenesis inhibitor (BAI1)-binding protein may be involved in neuronal growth-cone guidance.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • PurityIgG fraction
  • Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Primary antibody notesBrain-specific angiogenesis inhibitor (BAI1)-binding protein may be involved in neuronal growth-cone guidance.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab791 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Can be blocked with Human BAI1 associated protein 2 isoform 3 peptide (ab19041).

Target

  • RelevanceBAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.
  • Cellular localizationCell Membrane and Cytoplasmic
  • Database links
  • Alternative names
    • BAI associated protein 2 antibody
    • BAIAP2 antibody
    • BAP2 antibody
    • Insulin receptor substrate p53 antibody
    • Insulin receptor substrate p53/p58 antibody
    • Insulin receptor substrate protein of 53 kDa antibody
    • IRSp53 antibody
    • Protein BAP2 antibody
    see all

Anti-BAI1 associated protein 2 isoform 3 antibody images

  • ab791 staining (1µg/ml) of Human Brain (Cerebellum) lysate (RIPA buffer, 35��g total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.
  • Lane 1 : Anti-BAI1 associated protein 2 isoform 3 antibody (ab791) at 1 µg/ml
    Lane 2 : anti- DYKDDDDK Tag at 1/3000 dilution
    Lane 3 : Anti-BAI1 associated protein 2 isoform 3 antibody (ab791) at 1 mg/ml

    Lane 1 : HEK293 lysate in RIPA buffer over expressing Human BAIAP2 with DYKDDDDK tag at 10 µg
    Lane 2 : HEK293 lysate in RIPA buffer over expressing Human BAIAP2 with DYKDDDDK tag at 10 µg
    Lane 3 : Mock-transfected HEK293

References for Anti-BAI1 associated protein 2 isoform 3 antibody (ab791)

ab791 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. AB791 is "Goat polyclonal to BAI1 associated protein 2 isoform 3" and as we understand from your e-mail you are using Goat anti-Rabbit secondary. There seems to be some problem with the compatibility of the primary and t...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"