• Product nameAnti-BAIAP2 antibody
    See all BAIAP2 primary antibodies
  • Description
    Mouse monoclonal to BAIAP2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-513 of Human BAIAP2


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG2b
  • Light chain typekappa
  • Research areas


Our Abpromise guarantee covers the use of ab56588 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAdapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation.
    • Tissue specificityIsoform 1 and isoform 4 are expressed almost exclusively in brain. Isoform 4 is barely detectable in placenta, prostate and testis. A short isoform is ubiquitous, with the highest expression in liver, prostate, testis and placenta.
    • Sequence similaritiesContains 1 IMD (IRSp53/MIM homology) domain.
      Contains 1 SH3 domain.
    • DomainThe IMD domain forms a coiled coil. The isolated domain can induce actin bundling and filopodia formation. In the absence of G-proteins intramolecular interaction between the IMD and the SH3 domain gives rise to an auto-inhibited state of the protein. Interaction of the IMD with RAC1 or CDC42 leads to activation.
      The SH3 domain interacts with ATN1, BAI1, WASF1, WASF2, SHANK1, DIAPH1 and ENAH.
    • Post-translational
      Phosphorylated on tyrosine residues by INSR in response to insulin treatment.
    • Cellular localizationCytoplasm. Membrane. Cell projection > filopodium. Cell projection > ruffle. Detected throughout the cytoplasm in the absence of specific binding partners. Detected in filopodia and close to membrane ruffles.
    • Information by UniProt
    • Database links
    • Alternative names
      • BAI-associated protein 2 antibody
      • BAI1 associated protein 2 antibody
      • BAI1-associated protein 2 antibody
      • BAIAP 2 antibody
      • Baiap2 antibody
      • BAIP2_HUMAN antibody
      • BAP2 antibody
      • Brain-specific angiogenesis inhibitor 1-associated protein 2 antibody
      • Fas ligand-associated factor 3 antibody
      • FLAF3 antibody
      • Insulin receptor substrate p53 antibody
      • Insulin receptor substrate p53/p58 antibody
      • Insulin receptor substrate protein of 53 kDa antibody
      • IRS-58 antibody
      • IRSp53 antibody
      • IRSp53/58 antibody
      • Protein BAP2 antibody
      see all

    Anti-BAIAP2 antibody images

    • Western blot against tagged recombinant protein immunogen using ab56588 BAIAP2 antibody at 1ug/ml. Predicted band size of immunogen is 82 kDa

    References for Anti-BAIAP2 antibody (ab56588)

    ab56588 has not yet been referenced specifically in any publications.

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