For the best experience on the Abcam website please upgrade to a modern browser such as
Product name Anti-Bak antibody See all Bak primary antibodies
Rabbit polyclonal to Bak
Tested applications Suitable for:
WB, ELISA more details
Synthetic peptide (Human)
Storage instructions Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg 2+ and Ca 2+), 150mM Sodium chloride, pH 7.4
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 23 kDa.
Function In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
Tissue specificity Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
Sequence similarities Belongs to the Bcl-2 family.
Domain Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
Cellular localization Mitochondrion membrane.
Information by UniProt
Apoptosis regulator BAK antibody
BAK like antibody
Anti-Bak antibody images
Western blot - Bak antibody (ab53153)
All lanes : Anti-Bak antibody (ab53153) at 1/500 dilution Lane 1 : extracts from 293 cells, untreated Lane 2 : extracts from 293 cells, treated with the immunizing peptide Predicted band size : 23 kDa Observed band size : 23 kDa
References for Anti-Bak antibody (ab53153)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"