Anti-Bak antibody - Aminoterminal end (ab62486)


  • Product nameAnti-Bak antibody - Aminoterminal end
    See all Bak primary antibodies
  • Description
    Rabbit polyclonal to Bak - Aminoterminal end
  • SpecificityThis antibody reacts with Bak
  • Tested applicationsSuitable for: WB, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A 13 amino acid synthetic peptide from near the amino terminus of human Bak

  • Positive control
    • L1210 cell lysates and L1210 cells


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityIon Exchange Chromatography
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab62486 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 23 kDa).
ICC Use a concentration of 2 µg/ml.


  • FunctionIn the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
  • Tissue specificityExpressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
  • Sequence similaritiesBelongs to the Bcl-2 family.
  • DomainIntact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
  • Cellular localizationMitochondrion membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apoptosis regulator BAK antibody
    • BAK antibody
    • BAK like antibody
    • Bak NT antibody
    • BAK_HUMAN antibody
    • Bak1 antibody
    • Bcl 2 homologous antagonist/killer antibody
    • Bcl 2 like 7 protein antibody
    • Bcl-2 homologous antagonist/killer antibody
    • Bcl-2-like protein 7 antibody
    • BCL2 antagonist/killer 1 antibody
    • Bcl2 like 7 Protein antibody
    • Bcl2-L-7 antibody
    • BCL2L7 antibody
    • CDN1 antibody
    • Cell death inhibitor 1 antibody
    • MGC117255 antibody
    • MGC3887 antibody
    • NBak antibody
    • Pro apoptotic protein BAK antibody
    see all

Anti-Bak antibody - Aminoterminal end images

  • Lane 1 : Anti-Bak antibody - Aminoterminal end (ab62486) at 1 µg/ml
    Lane 2 : Anti-Bak antibody - Aminoterminal end (ab62486) at 2 µg/ml

    Lane 1 : L1210 cell lysates
    Lane 2 : L1210 cell lysates

    Lysates/proteins at 15 µg per lane.

    Anti rabbit IgG secondary antibody

    Predicted band size : 23 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)
  • Immunocytochemistry of Bak in L1210 cells with ab62486 antibody at 2 µg/ml.

References for Anti-Bak antibody - Aminoterminal end (ab62486)

ab62486 has not yet been referenced specifically in any publications.

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