Overview

  • Product name
  • Description
    Rabbit polyclonal to BANP
  • Tested applications
    Suitable for: IP, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Rabbit, Horse, Guinea pig, Cow, Dog, Chimpanzee, Rhesus monkey, Chinese hamster, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between residue 425 and the C-terminus (residue 469) of human BANP (TrEMBL entry Q96GJ7)

  • Positive control
    • Nuclear extract from HeLa cells

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 8mM PBS, 60mM Citrate, 150mM Tris, pH 7 to 8
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab72076 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP 1/200 - 1/2500.
IHC-P 1/2000 - 1/10000.
WB 1/10000 - 1/25000. Predicted molecular weight: 59 kDa.

Target

  • Function
    Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest.
  • Tissue specificity
    Down-regulated in breast cancer cell lines.
  • Sequence similarities
    Belongs to the BANP/SMAR1 family.
    Contains 1 BEN domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AAH09424 antibody
    • Banp antibody
    • BANP_HUMAN antibody
    • BEN domain-containing protein 1 antibody
    • BEND1 antibody
    • BTG3 associated nuclear protein isoform a antibody
    • Btg3-associated nuclear protein antibody
    • DKFZp761H172 antibody
    • FLJ 10177 antibody
    • FLJ 20538 antibody
    • FLJ10177 antibody
    • FLJ20538 antibody
    • Protein BANP antibody
    • Scaffold/Matrix associated region 1 antibody
    • Scaffold/matrix-associated region-1-binding protein antibody
    • SMAR 1 antibody
    • SMAR1 antibody
    • SMARBP 1 antibody
    • SMARBP1 antibody
    see all

Anti-BANP antibody images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung carcinoma (left) and mouse renal cell carcinoma (right) tissues labelling BANP with ab72076 at 1/5000 (0.2µg/ml). Setection: DAB.
  • All lanes : Anti-BANP antibody (ab72076) at 0.1 µg/ml

    Lane 1 : Nuclear extract from HeLa cells at 5 µg
    Lane 2 : Nuclear extract from HeLa cells at 20 µg


    Predicted band size : 59 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 150 kDa,250 kDa. We are unsure as to the identity of these extra bands.

References for Anti-BANP antibody (ab72076)

ab72076 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab72076.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up