• Product name
  • Description
    Rabbit polyclonal to BAPX1
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rabbit, Chicken, Guinea pig, Cow, Dog, Zebrafish
  • Immunogen

    Synthetic peptide (Mouse)

  • Positive control
    • Jurkat cell lysate.



Our Abpromise guarantee covers the use of ab56029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/62500.

WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • Function
    Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus.
  • Tissue specificity
    Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton.
  • Involvement in disease
    Defects in NKX3-2 are the cause of spondylo-megaepiphyseal-metaphyseal dysplasia (SMMD) [MIM:613330]. It is a skeletal dysplasia characterized by disproportionate short stature with a short and stiff neck and trunk, relatively long limbs that may show flexion contractures of the distal joints, delayed and impaired ossification of the vertebral bodies, the presence of large epiphysea ossification centers and wide growth plates in the long tubular bones and numerous pseudoepiphyses of the short tubular bones in hands and feet.
  • Sequence similarities
    Belongs to the NK-3 homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • Bagpipe homeobox 1 antibody
    • Bagpipe homeobox homolog 1 antibody
    • Bagpipe homeobox protein homolog 1 antibody
    • Bagpipe homeobox, Drosophila, homolog of, 1 antibody
    • BAPX 1 antibody
    • Homeobox protein NK-3 homolog B antibody
    • Homeobox protein Nkx 3.2 antibody
    • Homeobox protein Nkx-3.2 antibody
    • MGC138171 antibody
    • NK3 homeobox 2 antibody
    • NKX3 2 antibody
    • NKX3-2 antibody
    • NKX3.2 antibody
    • NKX3.2, mouse, homolog of antibody
    • NKX32_HUMAN antibody
    • NKX3B antibody
    • OTTHUMP00000115816 antibody
    • SMMD antibody
    see all

Anti-BAPX1 antibody images

  • Anti-BAPX1 antibody (ab56029) at 0.5 µg/ml + Jurkat cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 35 kDa
    Observed band size : 35 kDa
    Additional bands at : 30 kDa. We are unsure as to the identity of these extra bands.

References for Anti-BAPX1 antibody (ab56029)

This product has been referenced in:
  • Yamashita S  et al. Sox9 directly promotes Bapx1 gene expression to repress Runx2 in chondrocytes. Exp Cell Res 315:2231-40 (2009). Read more (PubMed: 19306868) »

See 1 Publication for this product

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