Anti-BarX2 antibody [BAR X2 8A7/1] (ab20128)
Key features and details
- Mouse monoclonal [BAR X2 8A7/1] to BarX2
- Suitable for: ELISA, IHC-P, ICC/IF, WB
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-BarX2 antibody [BAR X2 8A7/1] -
Description
Mouse monoclonal [BAR X2 8A7/1] to BarX2 -
Host species
Mouse -
Tested applications
Suitable for: ELISA, IHC-P, ICC/IF, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Fusion protein: MBP-tagged BarX2 (Human).
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General notes
BarX2 is a tumour suppressor gene that encodes for a transcription factor known to regulate transcription of cell adhesion molecules in the mouse.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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Purity
Protein A/G purified -
Primary antibody notes
BarX2 is a tumour suppressor gene that encodes for a transcription factor known to regulate transcription of cell adhesion molecules in the mouse. -
Clonality
Monoclonal -
Clone number
BAR X2 8A7/1 -
Myeloma
Sp2/0-Ag14 -
Isotype
IgG1 -
Light chain type
unknown -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab20128 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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IHC-P |
Use at an assay dependent concentration.
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ICC/IF |
Use at an assay dependent concentration.
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WB | (1) |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Function
Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia. -
Tissue specificity
Highly expressed in adult salivary gland and at much lower levels in mammary gland, kidney and placenta. -
Sequence similarities
Belongs to the BAR homeobox family.
Contains 1 homeobox DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 8538 Human
- Omim: 604823 Human
- SwissProt: Q9UMQ3 Human
- Unigene: 591944 Human
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Alternative names
- BarH like homeobox 2 antibody
- BarX 2 antibody
- BARX homeobox antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab20128 has been referenced in 1 publication.
- Yang F et al. miR-942 promotes tumor migration, invasion, and angiogenesis by regulating EMT via BARX2 in non-small-cell lung cancer. J Cell Physiol 234:23596-23607 (2019). PubMed: 31236953