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Anti-Bassoon antibody [SAP7F407] (ab82958)

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Overview

Product name

Anti-Bassoon antibody [SAP7F407]
See all Bassoon products (4) ...

Description

Mouse monoclonal [SAP7F407] to Bassoon

Tested applications

WB, IP, ICCmore details

Cross reactivity

Reacts with

Mouse, Rat

Immunogen

Recombinant rat Bassoon protein

Positive control

Rat brain tissue extract

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.09% Sodium Azide
Constituents: 50% Glycerol, PBS

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Clone number

SAP7F407

Isotype

IgG2a

Research areas

Neuroscience >> Cell Type Marker >> Neuron marker >> Synapse marker

  • Western blot - Bassoon antibody [SAP7F407] (ab82958)Western blot - Bassoon antibody [SAP7F407] (ab82958) image (enlarge)

  • Immunocytochemistry/ Immunofluorescence - Bassoon antibody [SAP7F407] (ab82958)Immunocytochemistry/ Immunofluorescence - Bassoon antibody [SAP7F407] (ab82958) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab82958 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses.

Tissue specificity

Exclusively expressed in brain.

Post-translational
modifications

Myristoylated. The N-terminal myristoylation is not sufficient for presynaptic localization.

Cellular localization

Cytoplasm. Cell junction > synapse > synaptosome. Cytoplasm > cytoskeleton. Localized to the active zone of presynaptic density.

Target information above from: UniProt accessionQ9UPA5 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Bassoon protein antibody
  • BSN antibody
  • BSN_HUMAN antibody
  • KIAA0434 antibody
  • Neuronal double zinc finger protein antibody
  • Presynaptic cytomatrix protein antibody
  • Protein bassoon antibody
  • Zinc finger protein 231 antibody
  • ZNF 231 antibody
  • ZNF231 antibody
see all

Database links

Anti-Bassoon antibody [SAP7F407] images:

  Western blot - Bassoon antibody [SAP7F407] (ab82958)

Western blot - Bassoon antibody [SAP7F407] (ab82958)

Anti-Bassoon antibody [SAP7F407] (ab82958) at 1/500 dilution + rat brain tissue extract
developed using the ECL technique

Predicted band size : 416 kDa

  Immunocytochemistry/ Immunofluorescence - Bassoon antibody [SAP7F407] (ab82958)

Immunocytochemistry/ Immunofluorescence - Bassoon antibody [SAP7F407] (ab82958)

Bassoon localization in the rat brain cerebellar molecular layer using Bassoon monoclonal antibody (ab82958).

References for Anti-Bassoon antibody [SAP7F407] (ab82958)

This product has been referenced in:

  • Ripley B  et al. Regulation of synaptic stability by AMPA receptor reverse signaling. Proc Natl Acad Sci U S A 108:367-72 (2011). ICC/IF.Read more (PubMed: 21173224) »
  • Medvedeva YV  et al. Mechanisms of prolonged presynaptic Ca2+ signaling and glutamate release induced by TRPV1 activation in rat sensory neurons. J Neurosci 28:5295-311 (2008).Read more (PubMed: 18480286) »

See all 2 publications for this product

Publishing research using ab82958? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"