Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.
Involvement in disease
Bardet-Biedl syndrome 12
Belongs to the TCP-1 chaperonin family. BBS12 subfamily.
Cell projection, cilium. Located within the basal body of the primary cilium of differentiating preadipocytes.