• Product nameAnti-BBS9 antibody
    See all BBS9 primary antibodies
  • Description
    Rabbit polyclonal to BBS9
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-310 of Human BBS9 (AAH32715.1).

  • Positive control
    • BBS9 transfected 293T cell line lysate.



Our Abpromise guarantee covers the use of ab118110 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa.


  • FunctionThe BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
  • Tissue specificityWidely expressed. Expressed in adult heart, skeletal muscle, lung, liver, kidney, placenta and brain, and in fetal kidney, lung, liver and brain.
  • Involvement in diseaseA chromosomal aberration involving PTHB1 is found in Wilms tumor 5 (WT5) [MIM:601583]. Translocation t(1;7)(q42;p15) with OBSCN.
    Defects in BBS9 are a cause of Bardet-Biedl syndrome type 9 (BBS9) [MIM:209900]. Bardet-Biedl syndrome (BBS) is a genetically heterogeneous, autosomal recessive disorder characterized by usually severe pigmentary retinopathy, early onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation.
  • Cellular localizationCytoplasm > cytoskeleton > centrosome. Cell projection > cilium membrane. Cytoplasm. Localizes to nonmembranous centriolar satellites in the cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • B1 antibody
    • Bardet Biedl syndrome 9 antibody
    • Bardet-Biedl syndrome 9 protein antibody
    • bbs9 antibody
    • C18 antibody
    • D1 antibody
    • MGC118917 antibody
    • OTTHUMP00000158833 antibody
    • OTTHUMP00000202918 antibody
    • OTTHUMP00000202919 antibody
    • OTTHUMP00000202920 antibody
    • Parathyroid hormone-responsive B1 gene protein antibody
    • Protein PTHB1 antibody
    • PTH-responsive osteosarcoma B1 protein antibody
    • PTHB1 antibody
    • PTHB1_HUMAN antibody
    see all

Anti-BBS9 antibody images

  • All lanes : Anti-BBS9 antibody (ab118110) at 1 µg/ml

    Lane 1 : BBS9 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    developed using the ECL technique

    Predicted band size : 35 kDa

References for Anti-BBS9 antibody (ab118110)

ab118110 has not yet been referenced specifically in any publications.

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