Overview

  • Product name
    BC-11-38
  • Description
    Potent, selective PDE-11 inhibitor
  • Alternative names
    • BC11-38
  • Biological description

    Potent, selective inhibitor phosphodiesterase PDE-11 inhibitor (IC50 = 0.28 μM). IC50s for PDE1-10 are greater than 100 μM. Significantly elevates cAMP levels and cortisol production in H295R human adenocarcinoma cells.

Properties

  • Molecular weight
    304.43
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C15H16N2OS2
  • CAS Number
    686770-80-9
  • Storage instructions
    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    O=C1C=3SCCC=3N=C(SCCC)N1c2ccccc2
  • Source

    Synthetic

References

This product has been referenced in:
  • Ceyhan O  et al. Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen. Chem Biol 19:155-63 (2012). Read more (PubMed: 22284362) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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