Overview

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline. pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab21705 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 µg/ml.
ELISA Use at an assay dependent dilution.

Target

  • Function
    May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins.
  • Tissue specificity
    Ubiquitously expressed. Found in several cancer cell lines, but not in nonmalignant breast tissue.
  • Sequence similarities
    Contains 1 Ras-GEF domain.
    Contains 1 SH2 domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • BCAR 3 antibody
    • BCAR3 antibody
    • BCAR3_HUMAN antibody
    • Breast cancer anti estrogen resistance 3 antibody
    • Breast cancer anti estrogen resistance protein 3 antibody
    • Breast cancer anti-estrogen resistance protein 3 antibody
    • Breast cancer antiestrogen resistance 3 antibody
    • dJ1033H22.2 antibody
    • dJ1033H22.2 breast cancer anti estrogen resistance 3 antibody
    • dJ1033H22.2 breast cancer antiestrogen resistance 3 antibody
    • KIAA0554 antibody
    • Novel SH2 containing protein 2 antibody
    • Novel SH2-containing protein 2 antibody
    • NSP 2 antibody
    • NSP2 antibody
    • SH2 containing protein Nsp2 antibody
    • SH2 domain containing protein 3B antibody
    • SH2 domain-containing protein 3B antibody
    • SH2D3B antibody
    see all

Images

  • Anti-BCAR3 antibody (ab21705) at 0.5 µg/ml + Cell lysates prepared from mouse kidney epithelial cells at 15 µg

References

ab21705 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for your enquiry. We do not routinely offer free or trial sized samples for testing purposes. Goat polyclonal to BCAR3 (ab21705) is a fast track antibody and therefore as you mention any new details of application and species reactivity i...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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