The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100. Detects a band of approximately 106 kDa (predicted molecular weight: 101 kDa).
Use at an assay dependent dilution.
Tissue specificityExpressed in stomach, liver, lung, kidney, prostate, testis, thyroid gland, adrenal gland, brain, heart, skeletal muscle, colon, spleen, small intestine, placenta, blood leukocyte and mammary epithelial cells. Overexpressed in most breast cancer cell lines.
Involvement in diseaseNote=A chromosomal aberration involving BCAS3 has been found in some breast carcinoma cell lines. Translocation t(17;20)(q23;q13) with BCAS4.
Sequence similaritiesBelongs to the WD repeat BCAS3 family. Contains 3 WD repeats.