The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
FunctionMay promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
Tissue specificityExpressed at high levels in testis and skeletal muscle and at lower levels in brain, heart, kidney, liver, lung, ovary, pancreas, placenta, and spleen.
Sequence similaritiesBelongs to the BCP1 family.
Developmental stageIsoform 1 is expressed throughout the cell cycle. Isoform 2 is expressed following mitosis and peaks in the G1/S phase of the cell cycle.
Cellular localizationNucleus. Colocalizes with BRCA2 in discrete nuclear foci.
ab113288, at 1/100 dilution, staining BCCIP in formalin-fixed, paraffin-embedded Human breast carcinoma by Immunohistochemistry. Detection: Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain cross-adsorbed Antibody DyLight® 594 Conjugated used at a dilution of 1/100.
References for Anti-BCCIP antibody (ab113288)
has not yet been referenced specifically in any publications.
Publishing research using ab113288? Please let us know so that we can cite the reference in this datasheet.
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