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Goat polyclonal to Bcl 7A
This antibody is expected to recognize both reported isoforms (NP_066273.1; NP_001019979.1).
HumanPredicted to work with:
Mouse, Rat, Cow, Dog, Pig
Synthetic peptide: MKLEASQQNSEEM, corresponding to C terminal amino acids 219-231 of Human Bcl 7A.
This protein is similar to the actin-binding protein caldesmon.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration information loading...
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Immunizing Peptide (Blocking)
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 25 kDa).Can be blocked with Human Bcl 7A peptide (ab22792).
Involvement in disease
Note=Chromosomal aberrations involving BCL7A may be a cause of B-cell non-Hodgkin lymphoma. Three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) with MYC and with immunoglobulin gene regions.
Belongs to the BCL7 family.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
- B cell CLL/lymphoma 7 antibody
- B cell CLL/lymphoma 7 protein family member A antibody
- B cell CLL/lymphoma 7A antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"