Overview

  • Product name
  • Description
    Goat polyclonal to Bcl 7A
  • Specificity
    This antibody is expected to recognize both reported isoforms (NP_066273.1; NP_001019979.1).
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog, Pig
  • Immunogen

    Synthetic peptide: MKLEASQQNSEEM, corresponding to C terminal amino acids 219-231 of Human Bcl 7A.

  • Positive control
    • Human lymph node lysate.
  • General notes
    This protein is similar to the actin-binding protein caldesmon.

Properties

Applications

Our Abpromise guarantee covers the use of ab1075 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 25 kDa).Can be blocked with Human Bcl 7A peptide (ab22792).

Target

  • Involvement in disease
    Note=Chromosomal aberrations involving BCL7A may be a cause of B-cell non-Hodgkin lymphoma. Three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) with MYC and with immunoglobulin gene regions.
  • Sequence similarities
    Belongs to the BCL7 family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt
  • Database links
  • Alternative names
    • B cell CLL/lymphoma 7 antibody
    • B cell CLL/lymphoma 7 protein family member A antibody
    • B cell CLL/lymphoma 7A antibody
    • B-cell CLL/lymphoma 7 protein family member A antibody
    • BCL 7 antibody
    • BCL7 antibody
    • bcl7a antibody
    • BCL7A_HUMAN antibody
    see all

Images

References

ab1075 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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