For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Goat polyclonal to Bcl 7A
This antibody is expected to recognize both reported isoforms (NP_066273.1; NP_001019979.1).
HumanPredicted to work with:
Mouse, Rat, Cow, Dog, Pig
Synthetic peptide: MKLEASQQNSEEM, corresponding to C terminal amino acids 219-231 of Human Bcl 7A.
This protein is similar to the actin-binding protein caldesmon.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration information loading...
Immunogen affinity purified
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 25 kDa).Can be blocked with Human Bcl 7A peptide (ab22792).
Involvement in disease
Note=Chromosomal aberrations involving BCL7A may be a cause of B-cell non-Hodgkin lymphoma. Three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) with MYC and with immunoglobulin gene regions.
Belongs to the BCL7 family.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
- B cell CLL/lymphoma 7 antibody
- B cell CLL/lymphoma 7 protein family member A antibody
- B cell CLL/lymphoma 7A antibody
Western blot - Bcl 7A antibody (ab1075)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"