Overview

  • Product name
  • Description
    Goat polyclonal to Bcl2A1
  • Specificity
    ab106825 is expected to recognize both reported isoforms (NP_004040.1; NP_001108207.1).
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Dog
  • Immunogen

    Synthetic peptide:

    C-NVVSVDTART

    , corresponding to internal sequence amino acids 60-69 of Human Bcl2A1 (NP_004040.1)

  • Positive control
    • Human bone marrow lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab106825 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106825 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).

Target

  • Function
    Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection.
  • Tissue specificity
    Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.
  • Sequence similarities
    Belongs to the Bcl-2 family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACC 1 antibody
    • ACC 2 antibody
    • B2LA1_HUMAN antibody
    • Bcl 2 related protein A1 antibody
    • Bcl-2-like protein 5 antibody
    • Bcl-2-related protein A1 antibody
    • BCL2 related protein A1 antibody
    • Bcl2-L-5 antibody
    • BCL2A1 antibody
    • BCL2L5 antibody
    • BFL1 antibody
    • GRS antibody
    • HBPA1 antibody
    • Hematopoietic BCL2 related protein A1 antibody
    • Hemopoietic specific early response protein antibody
    • Hemopoietic-specific early response protein antibody
    • Protein BFL 1 antibody
    • Protein BFL-1 antibody
    • Protein GRS antibody
    see all

Images

  • Anti-Bcl2A1 antibody (ab106825) at 0.2 µg/ml + Human Bone Marrow lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 20 kDa
    Observed band size : 20 kDa

References

ab106825 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab106825.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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