Overview

  • Product nameAnti-Bcl2A1 antibody
    See all Bcl2A1 primary antibodies
  • Description
    Rabbit polyclonal to Bcl2A1
  • SpecificityThis antibody recognises human Bcl2A1 and to a lesser extent mouse Bcl2A1.
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    GST Fusion protein of human Bcl2A1 minus the transmembrane segment.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: PBS
  • PurityWhole antiserum
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab75887 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IP
  • Application notesIP: Use 1-2µl per IP from 10-50 million cells.
    WB: 1/1000. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).

    Tested on transfected cells and endogenous protein in various lympoid cell lines.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionRetards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection.
    • Tissue specificitySeems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.
    • Sequence similaritiesBelongs to the Bcl-2 family.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • ACC 1 antibody
      • ACC 2 antibody
      • B2LA1_HUMAN antibody
      • Bcl 2 related protein A1 antibody
      • Bcl-2-like protein 5 antibody
      • Bcl-2-related protein A1 antibody
      • BCL2 related protein A1 antibody
      • Bcl2-L-5 antibody
      • BCL2A1 antibody
      • BCL2L5 antibody
      • BFL1 antibody
      • GRS antibody
      • HBPA1 antibody
      • Hematopoietic BCL2 related protein A1 antibody
      • Hemopoietic specific early response protein antibody
      • Hemopoietic-specific early response protein antibody
      • Protein BFL 1 antibody
      • Protein BFL-1 antibody
      • Protein GRS antibody
      see all

    Anti-Bcl2A1 antibody images



    • Predicted band size : 20 kDa
      Observed band size : 20 kDa
    • Lanes 1-4: Immunoprecipitates with:

      Lane 1: Ab75887
      Lane 2: Normal rabbit serum
      Lane 3: Anti-HA monoclonal 12CA5
      Lane 4: Normal rabbit serum
      Lane 5: Total lysate

      Lanes 6-9: immunoprecipitates with:

      Lane 6: Ab75887
      Lane 7: Normal rabbit serum
      Lane 8: Anti-FLAG monoclonal M2
      Lane 9: Normal mouse serum
      Lane 10: Total lysate.


    • Predicted band size : 20 kDa

    References for Anti-Bcl2A1 antibody (ab75887)

    This product has been referenced in:
    • Chien WW  et al. Differential mechanisms of asparaginase resistance in B-type acute lymphoblastic leukemia and malignant natural killer cell lines. Sci Rep 5:8068 (2015). WB ; Human . Read more (PubMed: 25626693) »
    • Olsson Åkefeldt S  et al. Chemoresistance of human monocyte-derived dendritic cells is regulated by IL-17A. PLoS One 8:e56865 (2013). WB ; Human . Read more (PubMed: 23441221) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"